Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer
Cyclooxygenase 2 (COX2) can promote the synthesis of prostaglandins through metabolism, and is highly expressed in various tumor tissues including ovarian cancer. It can affect the occurrence and development of tumors in different ways by regulating downstream metabolites. It stimulates tumor cell p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
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Magazine House of Cancer Research on Prevention and Treatment
2019-11-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0413.htm |
| _version_ | 1819183053341196288 |
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| author | ZHANG Xiao YAN Keqin FENG Dingqing LING Bin |
| author_facet | ZHANG Xiao YAN Keqin FENG Dingqing LING Bin |
| author_sort | ZHANG Xiao |
| collection | DOAJ |
| description | Cyclooxygenase 2 (COX2) can promote the synthesis of prostaglandins through metabolism, and is highly expressed in various tumor tissues including ovarian cancer. It can affect the occurrence and development of tumors in different ways by regulating downstream metabolites. It stimulates tumor cell proliferation and migration, promotes angiogenesis, inhibits apoptosis, plays an important role in tumor progression and may provide new ideas for tumor therapy. |
| first_indexed | 2024-12-22T22:55:54Z |
| format | Article |
| id | doaj.art-6b4af5bda12b4224b4a030c3c6cb6a20 |
| institution | Directory Open Access Journal |
| issn | 1000-8578 1000-8578 |
| language | zho |
| last_indexed | 2024-12-22T22:55:54Z |
| publishDate | 2019-11-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj.art-6b4af5bda12b4224b4a030c3c6cb6a202022-12-21T18:09:50ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782019-11-0146111036103910.3971/j.issn.1000-8578.2019.19.04138578.2019.19.0413Advances in Role of Cyclooxygenase 2 in Development and Progression of CancerZHANG Xiao0YAN Keqin1FENG Dingqing2LING Bin3Department of Gynaecology and Obstetrics, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Gynaecology and Obstetrics, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Gynaecology and Obstetrics, China-Japan Friendship Hospital, Beijing 100029, ChinaDepartment of Gynaecology and Obstetrics, China-Japan Friendship Hospital, Beijing 100029, ChinaCyclooxygenase 2 (COX2) can promote the synthesis of prostaglandins through metabolism, and is highly expressed in various tumor tissues including ovarian cancer. It can affect the occurrence and development of tumors in different ways by regulating downstream metabolites. It stimulates tumor cell proliferation and migration, promotes angiogenesis, inhibits apoptosis, plays an important role in tumor progression and may provide new ideas for tumor therapy.http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0413.htmcox2apoptosiscancerovarian cancertherapy |
| spellingShingle | ZHANG Xiao YAN Keqin FENG Dingqing LING Bin Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer Zhongliu Fangzhi Yanjiu cox2 apoptosis cancer ovarian cancer therapy |
| title | Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer |
| title_full | Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer |
| title_fullStr | Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer |
| title_full_unstemmed | Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer |
| title_short | Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer |
| title_sort | advances in role of cyclooxygenase 2 in development and progression of cancer |
| topic | cox2 apoptosis cancer ovarian cancer therapy |
| url | http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0413.htm |
| work_keys_str_mv | AT zhangxiao advancesinroleofcyclooxygenase2indevelopmentandprogressionofcancer AT yankeqin advancesinroleofcyclooxygenase2indevelopmentandprogressionofcancer AT fengdingqing advancesinroleofcyclooxygenase2indevelopmentandprogressionofcancer AT lingbin advancesinroleofcyclooxygenase2indevelopmentandprogressionofcancer |