Deep learning-assisted IoMT framework for cerebral microbleed detection

The Internet of Things (IoT), big data, and artificial intelligence (AI) are all key technologies that influence the formation and implementation of digital medical services. Building Internet of Medical Things (IoMT) systems that combine advanced sensors with AI-powered insights is critical for int...

Full description

Bibliographic Details
Main Authors: Zeeshan Ali, Sheneela Naz, Sadaf Yasmin, Maryam Bukhari, Mucheol Kim
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023100879
_version_ 1797383936325713920
author Zeeshan Ali
Sheneela Naz
Sadaf Yasmin
Maryam Bukhari
Mucheol Kim
author_facet Zeeshan Ali
Sheneela Naz
Sadaf Yasmin
Maryam Bukhari
Mucheol Kim
author_sort Zeeshan Ali
collection DOAJ
description The Internet of Things (IoT), big data, and artificial intelligence (AI) are all key technologies that influence the formation and implementation of digital medical services. Building Internet of Medical Things (IoMT) systems that combine advanced sensors with AI-powered insights is critical for intelligent medical systems. This paper presents an IoMT framework for brain magnetic resonance imaging (MRI) analysis to lessen the unavoidable diagnosis and therapy faults that occur in human clinical settings for the accurate detection of cerebral microbleeds (CMBs). The problems in accurate CMB detection include that CMBs are tiny dots 5–10 mm in diameter; they are similar to healthy tissues and are exceedingly difficult to identify, necessitating specialist guidance in remote and underdeveloped medical centers. Secondly, in the existing studies, computer-aided diagnostic (CAD) systems are designed for accurate CMB detection, however, their proposed approaches consist of two stages. Potential candidate CMBs from the complete MRI image are selected in the first stage and then passed to the phase of false-positive reduction. These pre-and post-processing steps make it difficult to build a completely automated CAD system for CMB that can produce results without human intervention. Hence, as a key goal of this work, an end-to-end enhanced UNet-based model for effective CMB detection and segmentation for IoMT devices is proposed. The proposed system requires no pre-processing or post-processing steps for CMB segmentation, and no existing research localizes each CMB pixel from the complete MRI image input. The findings indicate that the suggested method outperforms in detecting CMBs in the presence of contrast variations and similarities with other normal tissues and yields a good dice score of 0.70, an accuracy of 99 %, as well as a false-positive rate of 0.002 %.© 2017 Elsevier Inc. All rights reserved.
first_indexed 2024-03-08T21:28:12Z
format Article
id doaj.art-6b4d6889c43a4603a1384d5a5ff84d4b
institution Directory Open Access Journal
issn 2405-8440
language English
last_indexed 2024-03-08T21:28:12Z
publishDate 2023-12-01
publisher Elsevier
record_format Article
series Heliyon
spelling doaj.art-6b4d6889c43a4603a1384d5a5ff84d4b2023-12-21T07:34:59ZengElsevierHeliyon2405-84402023-12-01912e22879Deep learning-assisted IoMT framework for cerebral microbleed detectionZeeshan Ali0Sheneela Naz1Sadaf Yasmin2Maryam Bukhari3Mucheol Kim4Research and Development Setups, National University of Computer and Emerging Sciences, Islamabad, 44000, PakistanDepartment of Computer Science, COMSATS University Islamabad, Islamabad, 45550, PakistanDepartment of Computer Science, COMSATS University Islamabad, Attock Campus, Attock, 43600, PakistanDepartment of Computer Science, COMSATS University Islamabad, Attock Campus, Attock, 43600, PakistanSchool of Computer Science and Engineering, Chung-Ang University, Seoul, 06974, South Korea; Corresponding author.The Internet of Things (IoT), big data, and artificial intelligence (AI) are all key technologies that influence the formation and implementation of digital medical services. Building Internet of Medical Things (IoMT) systems that combine advanced sensors with AI-powered insights is critical for intelligent medical systems. This paper presents an IoMT framework for brain magnetic resonance imaging (MRI) analysis to lessen the unavoidable diagnosis and therapy faults that occur in human clinical settings for the accurate detection of cerebral microbleeds (CMBs). The problems in accurate CMB detection include that CMBs are tiny dots 5–10 mm in diameter; they are similar to healthy tissues and are exceedingly difficult to identify, necessitating specialist guidance in remote and underdeveloped medical centers. Secondly, in the existing studies, computer-aided diagnostic (CAD) systems are designed for accurate CMB detection, however, their proposed approaches consist of two stages. Potential candidate CMBs from the complete MRI image are selected in the first stage and then passed to the phase of false-positive reduction. These pre-and post-processing steps make it difficult to build a completely automated CAD system for CMB that can produce results without human intervention. Hence, as a key goal of this work, an end-to-end enhanced UNet-based model for effective CMB detection and segmentation for IoMT devices is proposed. The proposed system requires no pre-processing or post-processing steps for CMB segmentation, and no existing research localizes each CMB pixel from the complete MRI image input. The findings indicate that the suggested method outperforms in detecting CMBs in the presence of contrast variations and similarities with other normal tissues and yields a good dice score of 0.70, an accuracy of 99 %, as well as a false-positive rate of 0.002 %.© 2017 Elsevier Inc. All rights reserved.http://www.sciencedirect.com/science/article/pii/S2405844023100879Cerebral microbleed (CMB) segmentationInternet of medical thingsComputer-aided diagnostic (CAD) systemsDeep learningUNet
spellingShingle Zeeshan Ali
Sheneela Naz
Sadaf Yasmin
Maryam Bukhari
Mucheol Kim
Deep learning-assisted IoMT framework for cerebral microbleed detection
Heliyon
Cerebral microbleed (CMB) segmentation
Internet of medical things
Computer-aided diagnostic (CAD) systems
Deep learning
UNet
title Deep learning-assisted IoMT framework for cerebral microbleed detection
title_full Deep learning-assisted IoMT framework for cerebral microbleed detection
title_fullStr Deep learning-assisted IoMT framework for cerebral microbleed detection
title_full_unstemmed Deep learning-assisted IoMT framework for cerebral microbleed detection
title_short Deep learning-assisted IoMT framework for cerebral microbleed detection
title_sort deep learning assisted iomt framework for cerebral microbleed detection
topic Cerebral microbleed (CMB) segmentation
Internet of medical things
Computer-aided diagnostic (CAD) systems
Deep learning
UNet
url http://www.sciencedirect.com/science/article/pii/S2405844023100879
work_keys_str_mv AT zeeshanali deeplearningassistediomtframeworkforcerebralmicrobleeddetection
AT sheneelanaz deeplearningassistediomtframeworkforcerebralmicrobleeddetection
AT sadafyasmin deeplearningassistediomtframeworkforcerebralmicrobleeddetection
AT maryambukhari deeplearningassistediomtframeworkforcerebralmicrobleeddetection
AT mucheolkim deeplearningassistediomtframeworkforcerebralmicrobleeddetection