Prevalence of UL97 gene mutations and polymorphisms in cytomegalovirus infection in the colon associated with or without ulcerative colitis

Prevalence of UL97 gene mutations and polymorphisms in cytomegalovirus infection in the colon associated with or without ulcerative colitis

Abstract Cytomegalovirus (CMV) reactivation in the colon is common in patients with severe ulcerative colitis (UC). Ganciclovir (GCV) resistance conferring CMV UL97 gene mutations have been reported in recent years. However, the prevalence of UL97 gene mutations in GCV-naive CMV infection in the col...

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Bibliographic Details
Main Authors: Satoshi Tamura, Satoshi Osawa, Natsuki Ishida, Takahiro Miyazu, Shinya Tani, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Isao Kosugi, Takahisa Furuta, Ken Sugimoto
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93168-x

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