Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido

ABSTRACT: Introduction: Decreased libido in middle-aged and elderly men is often difficult to treat, and identifying the risk factors affecting decreased libido is important for the clinical management of decreased libido. However, limited information is available regarding specific risk factors in...

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Main Authors: Kazuyoshi Shigehara, MD, PhD, Yuki Kato, MD, Masashi Iijima, MD, PhD, Shohei Kawaguchi, MD, PhD, Takahiro Nohara, MD, PhD, Kouji Izumi, MD, PhD, Yoshifumi Kadono, MD, PhD, Mikio Namiki, MD, PhD, Atsushi Mizokami, MD, PhD
Format: Article
Language:English
Published: Oxford University Press 2021-10-01
Series:Sexual Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2050116121001069
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author Kazuyoshi Shigehara, MD, PhD
Yuki Kato, MD
Masashi Iijima, MD, PhD
Shohei Kawaguchi, MD, PhD
Takahiro Nohara, MD, PhD
Kouji Izumi, MD, PhD
Yoshifumi Kadono, MD, PhD
Mikio Namiki, MD, PhD
Atsushi Mizokami, MD, PhD
author_facet Kazuyoshi Shigehara, MD, PhD
Yuki Kato, MD
Masashi Iijima, MD, PhD
Shohei Kawaguchi, MD, PhD
Takahiro Nohara, MD, PhD
Kouji Izumi, MD, PhD
Yoshifumi Kadono, MD, PhD
Mikio Namiki, MD, PhD
Atsushi Mizokami, MD, PhD
author_sort Kazuyoshi Shigehara, MD, PhD
collection DOAJ
description ABSTRACT: Introduction: Decreased libido in middle-aged and elderly men is often difficult to treat, and identifying the risk factors affecting decreased libido is important for the clinical management of decreased libido. However, limited information is available regarding specific risk factors in this population. Aim: The present study investigated the risk factors for decreased libido among middle-aged and elderly men. Methods: Patients who attended our male andropausal outpatient clinic between 2009 and 2015 were enrolled. All patients completed a self-administered questionnaire, which included the Aging Male Symptoms (AMS) scale, International Prostate Symptom Score (IPSS), and Sexual Health Inventory for Men (SHIM). Information on waist size, body mass index, present illness, present use of any medication, and lifestyle habits were collected by each attending physician. Blood biochemical data such as free testosterone, total cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-Chol), and hemoglobin A1c values were assessed. Libido was assessed based on AMS scale question 17, and a score of 4 or higher was defined as severely decreased libido (severe group). Main Outcome Measure: The clinical factors associated with severely decreased libido were analyzed based on multiple regression analysis. Results: A total of 292 subjects were included in the analysis, 111 (38%) of which belonged to the severe group. The mean age of study subjects was 66.2 years, and the mean FT value was 7.1 ± 2.2. Comparisons of each variable among the severe and not severe groups showed significant differences in older age, current cigarette smoking, AMS scale, IPSS, frequency of nocturnal voiding, SHIM score, and HDL-Chol value. Multivariate regression analysis revealed that current cigarette smoking, frequent nocturnal voiding, and a low SHIM score were the independent risk factors for severely decreased libido. Furthermore, the frequency of nocturnal voiding significantly increased with severity of decreased libido. Conclusion: Current cigarette smoking, frequent nocturnal voiding, and a low SHIM score were the independent risk factors for a severely low libido.K Shigehara, Y Kato, M Iijima, et al. Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido. Sex Med 2021;9:100426.
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spelling doaj.art-6b4dc4ab3fd443188302a809e42756532023-09-03T06:34:29ZengOxford University PressSexual Medicine2050-11612021-10-0195100426Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased LibidoKazuyoshi Shigehara, MD, PhD0Yuki Kato, MD1Masashi Iijima, MD, PhD2Shohei Kawaguchi, MD, PhD3Takahiro Nohara, MD, PhD4Kouji Izumi, MD, PhD5Yoshifumi Kadono, MD, PhD6Mikio Namiki, MD, PhD7Atsushi Mizokami, MD, PhD8Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan; Corresponding Author: Kazuyoshi Shigehara, MD, PhD, Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan. Tel: +81-76-265-2393; Fax: +81-76-234-4261Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanDepartment of Urology, Hasegawa Hospital, Toyama, Toyama, JapanDepartment of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, JapanABSTRACT: Introduction: Decreased libido in middle-aged and elderly men is often difficult to treat, and identifying the risk factors affecting decreased libido is important for the clinical management of decreased libido. However, limited information is available regarding specific risk factors in this population. Aim: The present study investigated the risk factors for decreased libido among middle-aged and elderly men. Methods: Patients who attended our male andropausal outpatient clinic between 2009 and 2015 were enrolled. All patients completed a self-administered questionnaire, which included the Aging Male Symptoms (AMS) scale, International Prostate Symptom Score (IPSS), and Sexual Health Inventory for Men (SHIM). Information on waist size, body mass index, present illness, present use of any medication, and lifestyle habits were collected by each attending physician. Blood biochemical data such as free testosterone, total cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-Chol), and hemoglobin A1c values were assessed. Libido was assessed based on AMS scale question 17, and a score of 4 or higher was defined as severely decreased libido (severe group). Main Outcome Measure: The clinical factors associated with severely decreased libido were analyzed based on multiple regression analysis. Results: A total of 292 subjects were included in the analysis, 111 (38%) of which belonged to the severe group. The mean age of study subjects was 66.2 years, and the mean FT value was 7.1 ± 2.2. Comparisons of each variable among the severe and not severe groups showed significant differences in older age, current cigarette smoking, AMS scale, IPSS, frequency of nocturnal voiding, SHIM score, and HDL-Chol value. Multivariate regression analysis revealed that current cigarette smoking, frequent nocturnal voiding, and a low SHIM score were the independent risk factors for severely decreased libido. Furthermore, the frequency of nocturnal voiding significantly increased with severity of decreased libido. Conclusion: Current cigarette smoking, frequent nocturnal voiding, and a low SHIM score were the independent risk factors for a severely low libido.K Shigehara, Y Kato, M Iijima, et al. Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido. Sex Med 2021;9:100426.http://www.sciencedirect.com/science/article/pii/S2050116121001069Erectile DysfunctionLibidoNocturiaSmoking
spellingShingle Kazuyoshi Shigehara, MD, PhD
Yuki Kato, MD
Masashi Iijima, MD, PhD
Shohei Kawaguchi, MD, PhD
Takahiro Nohara, MD, PhD
Kouji Izumi, MD, PhD
Yoshifumi Kadono, MD, PhD
Mikio Namiki, MD, PhD
Atsushi Mizokami, MD, PhD
Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
Sexual Medicine
Erectile Dysfunction
Libido
Nocturia
Smoking
title Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
title_full Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
title_fullStr Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
title_full_unstemmed Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
title_short Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido
title_sort risk factors affecting decreased libido among middle aged to elderly men nocturnal voiding is an independent risk factor of decreased libido
topic Erectile Dysfunction
Libido
Nocturia
Smoking
url http://www.sciencedirect.com/science/article/pii/S2050116121001069
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