Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats
The status of antioxidant superoxide dismutase (SOD) was reported decreased in the liver tissues of diabetic experimental Macaca fascicularis. This study observed effect of Mamordica charantia on the status of SOD in the liver and kidney of diabetic experimental rats. The SOD was localized using imm...
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| Format: | Article |
| Language: | English |
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Bogor Agricultural University
2010-06-01
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| Series: | Hayati Journal of Biosciences |
| Subjects: | |
| Online Access: | http://journal.ipb.ac.id/index.php/hayati/article/view/1345/443 |
| _version_ | 1818956636998336512 |
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| author | TUTIK WRESDIYATI TEGUH SURANTA SINULINGGA YOLI ZULFANEDI |
| author_facet | TUTIK WRESDIYATI TEGUH SURANTA SINULINGGA YOLI ZULFANEDI |
| author_sort | TUTIK WRESDIYATI |
| collection | DOAJ |
| description | The status of antioxidant superoxide dismutase (SOD) was reported decreased in the liver tissues of diabetic experimental Macaca fascicularis. This study observed effect of Mamordica charantia on the status of SOD in the liver and kidney of diabetic experimental rats. The SOD was localized using immunohistochemical technique. Male Wistar rats of negative control and diabetes mellitus (DM) group treated with 5 and 10% of M. charantia powder for 28 days. The DM condition was achieved by alloxan (110 mg/kg BW) induction. Charantia powder increased the status of antioxidant SOD in the liver and kidney of diabetic experimental rats. Aplication of M. charantia powder 10% gave better results than that of 5%. The results suggested that M. charantia powder can increase the status of antioxidant in the oxidative stress condition, such as diabetes mellitus. |
| first_indexed | 2024-12-20T10:57:07Z |
| format | Article |
| id | doaj.art-6b547b8f4e2142a2bce0182332958a49 |
| institution | Directory Open Access Journal |
| issn | 1978-3019 2086-4094 |
| language | English |
| last_indexed | 2024-12-20T10:57:07Z |
| publishDate | 2010-06-01 |
| publisher | Bogor Agricultural University |
| record_format | Article |
| series | Hayati Journal of Biosciences |
| spelling | doaj.art-6b547b8f4e2142a2bce0182332958a492022-12-21T19:43:07ZengBogor Agricultural UniversityHayati Journal of Biosciences1978-30192086-40942010-06-011725357Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic RatsTUTIK WRESDIYATITEGUH SURANTA SINULINGGAYOLI ZULFANEDIThe status of antioxidant superoxide dismutase (SOD) was reported decreased in the liver tissues of diabetic experimental Macaca fascicularis. This study observed effect of Mamordica charantia on the status of SOD in the liver and kidney of diabetic experimental rats. The SOD was localized using immunohistochemical technique. Male Wistar rats of negative control and diabetes mellitus (DM) group treated with 5 and 10% of M. charantia powder for 28 days. The DM condition was achieved by alloxan (110 mg/kg BW) induction. Charantia powder increased the status of antioxidant SOD in the liver and kidney of diabetic experimental rats. Aplication of M. charantia powder 10% gave better results than that of 5%. The results suggested that M. charantia powder can increase the status of antioxidant in the oxidative stress condition, such as diabetes mellitus.http://journal.ipb.ac.id/index.php/hayati/article/view/1345/443Superoxide dismutase (SOD)Mamordica charantiadiabetes mellitusliverkidneyimmunohistochemistry |
| spellingShingle | TUTIK WRESDIYATI TEGUH SURANTA SINULINGGA YOLI ZULFANEDI Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats Hayati Journal of Biosciences Superoxide dismutase (SOD) Mamordica charantia diabetes mellitus liver kidney immunohistochemistry |
| title | Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats |
| title_full | Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats |
| title_fullStr | Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats |
| title_full_unstemmed | Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats |
| title_short | Effect of Mamordica charantia L. Powder on Antioxidant Superoxide Dismutase in Liver and Kidney of Diabetic Rats |
| title_sort | effect of mamordica charantia l powder on antioxidant superoxide dismutase in liver and kidney of diabetic rats |
| topic | Superoxide dismutase (SOD) Mamordica charantia diabetes mellitus liver kidney immunohistochemistry |
| url | http://journal.ipb.ac.id/index.php/hayati/article/view/1345/443 |
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