Choroidal thickness in healthy Egyptians and its correlation with age

Purpose The aim of this study was to investigate choroidal thickness in healthy Egyptians and its correlation with age. Patients and methods This cross-sectional study included 134 eyes of 89 healthy Egyptians who were divided into three age groups: group 1, 20–40 years old; group 2, 40–60 years old...

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Main Author: Mona K Abdellatif
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of the Egyptian Ophthalmological Society
Subjects:
Online Access:http://www.jeos.eg.net/article.asp?issn=2090-0686;year=2017;volume=110;issue=1;spage=22;epage=27;aulast=Abdellatif
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author Mona K Abdellatif
author_facet Mona K Abdellatif
author_sort Mona K Abdellatif
collection DOAJ
description Purpose The aim of this study was to investigate choroidal thickness in healthy Egyptians and its correlation with age. Patients and methods This cross-sectional study included 134 eyes of 89 healthy Egyptians who were divided into three age groups: group 1, 20–40 years old; group 2, 40–60 years old; and group 3, more than 60 years old. Spectral-domain optical coherence tomography using enhanced depth imaging was used to calculate choroidal thickness map in the macular area. Eyes with high myopia and hyperopia were excluded. Results The mean (±SD) central choroidal thickness was 337.23±37.51, 285.29±31.23, and 270.24±22.37 µm in groups 1, 2, and 3 consecutively (P<0.001). The choroidal thickness was highest in the central 1 mm zone, followed by the superior quadrant, and the thinnest quadrant was the nasal one in the three groups. Regression analysis showed significant choroidal thickening in group 1 (B=4.941, P=0.001), nonsignificant thinning in group 2 (B=−0.301, P=0.739), and significant thinning in group 3 (B=−3.774, P=0.001). Conclusion Choroidal thickness varies significantly with age. Significant choroidal thinning starts in the fifth decade of life, but is more statistically significant after the age of 60 years. This proves that choroidal thinning is not fixed in all age groups.
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spelling doaj.art-6b55b18fdc62494a94bcd9a20a44289d2022-12-21T22:36:22ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Ophthalmological Society2090-06862314-66482017-01-011101222710.4103/ejos.ejos_12_17Choroidal thickness in healthy Egyptians and its correlation with ageMona K AbdellatifPurpose The aim of this study was to investigate choroidal thickness in healthy Egyptians and its correlation with age. Patients and methods This cross-sectional study included 134 eyes of 89 healthy Egyptians who were divided into three age groups: group 1, 20–40 years old; group 2, 40–60 years old; and group 3, more than 60 years old. Spectral-domain optical coherence tomography using enhanced depth imaging was used to calculate choroidal thickness map in the macular area. Eyes with high myopia and hyperopia were excluded. Results The mean (±SD) central choroidal thickness was 337.23±37.51, 285.29±31.23, and 270.24±22.37 µm in groups 1, 2, and 3 consecutively (P<0.001). The choroidal thickness was highest in the central 1 mm zone, followed by the superior quadrant, and the thinnest quadrant was the nasal one in the three groups. Regression analysis showed significant choroidal thickening in group 1 (B=4.941, P=0.001), nonsignificant thinning in group 2 (B=−0.301, P=0.739), and significant thinning in group 3 (B=−3.774, P=0.001). Conclusion Choroidal thickness varies significantly with age. Significant choroidal thinning starts in the fifth decade of life, but is more statistically significant after the age of 60 years. This proves that choroidal thinning is not fixed in all age groups.http://www.jeos.eg.net/article.asp?issn=2090-0686;year=2017;volume=110;issue=1;spage=22;epage=27;aulast=Abdellatifagechoroidal thicknessenhanced depth imagingoptical coherence tomography
spellingShingle Mona K Abdellatif
Choroidal thickness in healthy Egyptians and its correlation with age
Journal of the Egyptian Ophthalmological Society
age
choroidal thickness
enhanced depth imaging
optical coherence tomography
title Choroidal thickness in healthy Egyptians and its correlation with age
title_full Choroidal thickness in healthy Egyptians and its correlation with age
title_fullStr Choroidal thickness in healthy Egyptians and its correlation with age
title_full_unstemmed Choroidal thickness in healthy Egyptians and its correlation with age
title_short Choroidal thickness in healthy Egyptians and its correlation with age
title_sort choroidal thickness in healthy egyptians and its correlation with age
topic age
choroidal thickness
enhanced depth imaging
optical coherence tomography
url http://www.jeos.eg.net/article.asp?issn=2090-0686;year=2017;volume=110;issue=1;spage=22;epage=27;aulast=Abdellatif
work_keys_str_mv AT monakabdellatif choroidalthicknessinhealthyegyptiansanditscorrelationwithage