Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis

Tramadol is a centrally-acting analgesic used for treating moderate to severe acute and chronic pain. Pain is an unpleasant sensation that occurs most commonly as a result of tissue injury. Tramadol possesses agonist actions at the μ-opioid receptor and effects reuptake at the noradrenergic and ser...

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Main Authors: Farideh Mousazadeh, Yar-Mohammad Baghelani, Shamsi Rahimi
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2023-04-01
Series:ADMET and DMPK
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/1593
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author Farideh Mousazadeh
Yar-Mohammad Baghelani
Shamsi Rahimi
author_facet Farideh Mousazadeh
Yar-Mohammad Baghelani
Shamsi Rahimi
author_sort Farideh Mousazadeh
collection DOAJ
description Tramadol is a centrally-acting analgesic used for treating moderate to severe acute and chronic pain. Pain is an unpleasant sensation that occurs most commonly as a result of tissue injury. Tramadol possesses agonist actions at the μ-opioid receptor and effects reuptake at the noradrenergic and serotonergic systems. In the last years, several analytical procedures have been published in the literature for the determination of tramadol from pharmaceutical formulations and biological matrices. Electrochemical methods have attracted tremendous attention for the quantification of this drug owing to their demonstrated potential for quick response, real-time measurements, elevated selectivity and sensitivity. In this review, we highlighted the recent advances and applications of nanomaterials-based electrochemical sensors for the analysis and detection of tramadol, which is extremely important for the indication of effective diagnoses and for quality control analyses in order to protect human health. Also, the main challenges in developing nanomaterials-based electrochemical sensors for the determination of tramadol will be discussed. At last, this review offers prospects for the future research and development needed for modified electrode sensing technology for the detection of tramadol.
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spelling doaj.art-6b56e1c2ab7f47068ce55110764b640f2023-04-26T20:18:04ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182023-04-0110.5599/admet.1593Recent advances in nanomaterials-based electrochemical sensors for tramadol analysisFarideh Mousazadeh0Yar-Mohammad Baghelani1Shamsi Rahimi2Department of Chemistry, Payame Noor University, Tehran, IranDepartment of Chemistry, Faculty of Sciences, Ilam University, Ilam, IranDepartment of Chemistry, Payame Noor University, Tehran, Iran Tramadol is a centrally-acting analgesic used for treating moderate to severe acute and chronic pain. Pain is an unpleasant sensation that occurs most commonly as a result of tissue injury. Tramadol possesses agonist actions at the μ-opioid receptor and effects reuptake at the noradrenergic and serotonergic systems. In the last years, several analytical procedures have been published in the literature for the determination of tramadol from pharmaceutical formulations and biological matrices. Electrochemical methods have attracted tremendous attention for the quantification of this drug owing to their demonstrated potential for quick response, real-time measurements, elevated selectivity and sensitivity. In this review, we highlighted the recent advances and applications of nanomaterials-based electrochemical sensors for the analysis and detection of tramadol, which is extremely important for the indication of effective diagnoses and for quality control analyses in order to protect human health. Also, the main challenges in developing nanomaterials-based electrochemical sensors for the determination of tramadol will be discussed. At last, this review offers prospects for the future research and development needed for modified electrode sensing technology for the detection of tramadol. https://pub.iapchem.org/ojs/index.php/admet/article/view/1593
spellingShingle Farideh Mousazadeh
Yar-Mohammad Baghelani
Shamsi Rahimi
Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
ADMET and DMPK
title Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
title_full Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
title_fullStr Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
title_full_unstemmed Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
title_short Recent advances in nanomaterials-based electrochemical sensors for tramadol analysis
title_sort recent advances in nanomaterials based electrochemical sensors for tramadol analysis
url https://pub.iapchem.org/ojs/index.php/admet/article/view/1593
work_keys_str_mv AT faridehmousazadeh recentadvancesinnanomaterialsbasedelectrochemicalsensorsfortramadolanalysis
AT yarmohammadbaghelani recentadvancesinnanomaterialsbasedelectrochemicalsensorsfortramadolanalysis
AT shamsirahimi recentadvancesinnanomaterialsbasedelectrochemicalsensorsfortramadolanalysis