Sirtuins in intervertebral disc degeneration: current understanding

Sirtuins in intervertebral disc degeneration: current understanding

Abstract Background Intervertebral disc degeneration (IVDD) is one of the etiologic factors of degenerative spinal diseases, which can lead to a variety of pathological spinal conditions such as disc herniation, spinal stenosis, and scoliosis. IVDD is a leading cause of lower back pain, the prevalen...

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Bibliographic Details
Main Authors: Jianlin Shen, Yujian Lan, Ziyu Ji, Huan Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Molecular Medicine
Subjects:
SIRTs
Intervertebral disc degeneration
Autophagy
Apoptosis
Oxidative stress
Online Access:https://doi.org/10.1186/s10020-024-00811-0

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