Treatment of 3D In Vitro Tumoroids of Ovarian Cancer Using Photochemical Internalisation as a Drug Delivery Method

Treatment of 3D In Vitro Tumoroids of Ovarian Cancer Using Photochemical Internalisation as a Drug Delivery Method

Photochemical internalisation (PCI) is a means of achieving spatio-temporal control of cytosolic drug delivery using sub-lethal photodynamic therapy (PDT), with a photosensitiser that can be activated by non-ionising visible light. Various 3D models including those developed at our laboratory, where...

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Bibliographic Details
Main Authors: Layla Mohammad Hadi, Katerina Stamati, Elnaz Yaghini, Alexander J. MacRobert, Marilena Loizidou
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
ovarian cancer
photochemical internalisation
photodynamic therapy
tumouroids
3D compressed collagen construct
hypoxia
Online Access:https://www.mdpi.com/2227-9059/11/2/572

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https://www.mdpi.com/2227-9059/11/2/572

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