SorLA in astrocytes regulates blood-brain barrier integrity

SorLA in astrocytes regulates blood-brain barrier integrity

The brain`s homeostasis depends heavily on the integrity of the blood-brain barrier (BBB). Astrocytes are an essential part of the BBB in modulating and maintaining the barrier properties of the brain endothelial cells (BECs). Despite decades of research, the elements of glial regulation are not ful...

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Bibliographic Details
Main Authors: Andrea E. Toth, Adrian Klepe, Dora V. Lipka, Charlotte Goldeman, Birger Brodin, Morten S. Nielsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Drug Delivery
Subjects:
SorLA
SorL1
LR11
astrocytes
blood-brain barrier
claudin-5
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2022.1082689/full

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