Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry
A method was developed for the determination of amantadine sulfonamides, quinolones and chloramphenicols in cooked meat. The samples were extracted with acetonitrile-water mixtures (V:V=8:2), purified with PRiME HLB solid phase extraction column. 36 veterinary drugs were determined by ultra performa...
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| Format: | Article |
| Language: | zho |
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The editorial department of Science and Technology of Food Industry
2023-07-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080155 |
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| author | Fei ZHANG Yuan WANG Xiaoning MA Jinlei ZHANG Jingting GONG Mingxin FU |
| author_facet | Fei ZHANG Yuan WANG Xiaoning MA Jinlei ZHANG Jingting GONG Mingxin FU |
| author_sort | Fei ZHANG |
| collection | DOAJ |
| description | A method was developed for the determination of amantadine sulfonamides, quinolones and chloramphenicols in cooked meat. The samples were extracted with acetonitrile-water mixtures (V:V=8:2), purified with PRiME HLB solid phase extraction column. 36 veterinary drugs were determined by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) with an electrospray ion source (ESI±) in positive and negative ion switching scanning mode. The results showed that the 36 veterinary drugs showed a good linear relationship in the concentration range of 0.5~20.0 ng/mL (R2>0.999). The limits of detection were 0.10 μg/kg and the limits of quantitation were 0.33 μg/kg. The average recovery was 70.8%~106.9% in the range of high, medium and low concentrations (0.5, 1.0 and 5.0 μg/kg). The relative standard deviations (RSD, n=6) was 0.2%~6.2%. The method is simple, sensitive and accurate, and could be used for the determination of 36 veterinary drug residues in cooked meat. |
| first_indexed | 2024-03-12T13:34:22Z |
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| id | doaj.art-6b6428778b2b4b29a71a7c9040765442 |
| institution | Directory Open Access Journal |
| issn | 1002-0306 |
| language | zho |
| last_indexed | 2024-03-12T13:34:22Z |
| publishDate | 2023-07-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj.art-6b6428778b2b4b29a71a7c90407654422023-08-24T06:00:44ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-07-01441334034810.13386/j.issn1002-0306.20220801552022080155-13Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass SpectrometryFei ZHANG0Yuan WANG1Xiaoning MA2Jinlei ZHANG3Jingting GONG4Mingxin FU5Analysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaAnalysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaAnalysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaAnalysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaAnalysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaAnalysis and Testing Center, Xinjiang Academy of Agricultural Reclamation Science, Shihezi 832000, ChinaA method was developed for the determination of amantadine sulfonamides, quinolones and chloramphenicols in cooked meat. The samples were extracted with acetonitrile-water mixtures (V:V=8:2), purified with PRiME HLB solid phase extraction column. 36 veterinary drugs were determined by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) with an electrospray ion source (ESI±) in positive and negative ion switching scanning mode. The results showed that the 36 veterinary drugs showed a good linear relationship in the concentration range of 0.5~20.0 ng/mL (R2>0.999). The limits of detection were 0.10 μg/kg and the limits of quantitation were 0.33 μg/kg. The average recovery was 70.8%~106.9% in the range of high, medium and low concentrations (0.5, 1.0 and 5.0 μg/kg). The relative standard deviations (RSD, n=6) was 0.2%~6.2%. The method is simple, sensitive and accurate, and could be used for the determination of 36 veterinary drug residues in cooked meat.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080155ultra performance liquid chromatography-tandem mass spectrometrycooked meatprime hlb solid phase extractionveterinary drug residue |
| spellingShingle | Fei ZHANG Yuan WANG Xiaoning MA Jinlei ZHANG Jingting GONG Mingxin FU Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry Shipin gongye ke-ji ultra performance liquid chromatography-tandem mass spectrometry cooked meat prime hlb solid phase extraction veterinary drug residue |
| title | Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry |
| title_full | Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry |
| title_fullStr | Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry |
| title_full_unstemmed | Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry |
| title_short | Determination of 36 Veterinary Drug Residues in Cooked Meat by Ultra Performance Liquid Chromatography-tandem Mass Spectrometry |
| title_sort | determination of 36 veterinary drug residues in cooked meat by ultra performance liquid chromatography tandem mass spectrometry |
| topic | ultra performance liquid chromatography-tandem mass spectrometry cooked meat prime hlb solid phase extraction veterinary drug residue |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080155 |
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