Short-Term and Long-Term FK506 Treatment Alters the Vascular Reactivity of Renal and Mesenteric Vascular Beds

The aims of this study were to investigate the role of endothelin-1 in FK506-induced hypertension and vascular dysfunction of rats treated with the drug for 8 (short-term) or 30 (long-term) days and to measure malondialdehyde levels in the kidneys. Kidney and mesentery of rats were perfused. In the...

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Bibliographic Details
Main Authors: Guray Soydan, Ender Tekes, Meral Tuncer
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319343488