Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network
Spiking regularity in a clustered Hodgkin–Huxley (HH) neuronal network has been studied in this letter. A stochastic HH neuronal model with channel blocks has been applied as local neuronal model. Effects of the internal channel noise on the spiking regularity are discussed by changing the membrane...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-01-01
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| Series: | Theoretical and Applied Mechanics Letters |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095034915302877 |
| _version_ | 1818507011140091904 |
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| author | Xiaojuan Sun |
| author_facet | Xiaojuan Sun |
| author_sort | Xiaojuan Sun |
| collection | DOAJ |
| description | Spiking regularity in a clustered Hodgkin–Huxley (HH) neuronal network has been studied in this letter. A stochastic HH neuronal model with channel blocks has been applied as local neuronal model. Effects of the internal channel noise on the spiking regularity are discussed by changing the membrane patch size. We find that when there is no channel blocks in potassium channels, there exist some intermediate membrane patch sizes at which the spiking regularity could reach to a higher level. Spiking regularity increases with the membrane patch size when sodium channels are not blocked. Namely, depending on different channel blocking states, internal channel noise tuned by membrane patch size could have different influence on the spiking regularity of neuronal networks. |
| first_indexed | 2024-12-10T22:12:41Z |
| format | Article |
| id | doaj.art-6b6532967d65436a914fa46717fcb47e |
| institution | Directory Open Access Journal |
| issn | 2095-0349 |
| language | English |
| last_indexed | 2024-12-10T22:12:41Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Theoretical and Applied Mechanics Letters |
| spelling | doaj.art-6b6532967d65436a914fa46717fcb47e2022-12-22T01:31:34ZengElsevierTheoretical and Applied Mechanics Letters2095-03492014-01-014110.1063/2.1401305Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal networkXiaojuan SunSpiking regularity in a clustered Hodgkin–Huxley (HH) neuronal network has been studied in this letter. A stochastic HH neuronal model with channel blocks has been applied as local neuronal model. Effects of the internal channel noise on the spiking regularity are discussed by changing the membrane patch size. We find that when there is no channel blocks in potassium channels, there exist some intermediate membrane patch sizes at which the spiking regularity could reach to a higher level. Spiking regularity increases with the membrane patch size when sodium channels are not blocked. Namely, depending on different channel blocking states, internal channel noise tuned by membrane patch size could have different influence on the spiking regularity of neuronal networks.http://www.sciencedirect.com/science/article/pii/S2095034915302877spiking regularityinternal noiseclustered neuronal networkHodgkin—Huxley neuron |
| spellingShingle | Xiaojuan Sun Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network Theoretical and Applied Mechanics Letters spiking regularity internal noise clustered neuronal network Hodgkin—Huxley neuron |
| title | Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network |
| title_full | Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network |
| title_fullStr | Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network |
| title_full_unstemmed | Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network |
| title_short | Effects of internal noise on the spiking regularity of a clustered Hodgkin-Huxley neuronal network |
| title_sort | effects of internal noise on the spiking regularity of a clustered hodgkin huxley neuronal network |
| topic | spiking regularity internal noise clustered neuronal network Hodgkin—Huxley neuron |
| url | http://www.sciencedirect.com/science/article/pii/S2095034915302877 |
| work_keys_str_mv | AT xiaojuansun effectsofinternalnoiseonthespikingregularityofaclusteredhodgkinhuxleyneuronalnetwork |