Targeting Oncogenic Protein-Protein Interactions by Diversity Oriented Synthesis and Combinatorial Chemistry Approaches

Targeting Oncogenic Protein-Protein Interactions by Diversity Oriented Synthesis and Combinatorial Chemistry Approaches

We are currently witnessing a decline in the development of efficient new anticancer drugs, despite the salient efforts made on all fronts of cancer drug discovery. This trend presumably relates to the substantial heterogeneity and the inherent biological complexity of cancer, which hinder drug deve...

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Bibliographic Details
Main Authors: Andreas G. Tzakos, Demosthenes Fokas, Charlie Johannes, Vassilios Moussis, Eleftheria Hatzimichael, Evangelos Briasoulis
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
diversity-oriented synthesis
combinatorial chemistry
protein-protein interactions
cancer
Online Access:http://www.mdpi.com/1420-3049/16/6/4408/

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