Case Report: Altered NK Cell Compartment and Reduced CXCR4 Chemotactic Response of B Lymphocytes in an Immunodeficient Patient With HPV-Related Disease

Case Report: Altered NK Cell Compartment and Reduced CXCR4 Chemotactic Response of B Lymphocytes in an Immunodeficient Patient With HPV-Related Disease

The study of inborn errors of immunity (IEI) provides unique opportunities to elucidate the microbiome and pathogenic mechanisms related to severe viral infection. Several immunological and genetic anomalies may contribute to the susceptibility to develop Human Papillomavirus (HPV) pathogenesis. The...

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Bibliographic Details
Main Authors: Margherita Doria, Giusella M. F. Moscato, Silvia Di Cesare, Gigliola Di Matteo, Mayla Sgrulletti, Françoise Bachelerie, Viviana Marin-Esteban, Viviana Moschese
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
WHIM
CXCR4/CXCL12 axis
B lymphocytes
NK cells
HPV
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.799564/full

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