Single nucleotide polymorphisms in C-reactive protein (CRP) predict response to adjunctive celecoxib treatment of resistant bipolar depression

Single nucleotide polymorphisms in C-reactive protein (CRP) predict response to adjunctive celecoxib treatment of resistant bipolar depression

Background: Affective illness has been associated with a proinflammatory state, and it is generally accepted that the immune system plays a key role in the pathophysiology of mood disorders. Since inflammatory biomarkers are elevated in bipolar disorder, anti-inflammatory combination therapies may e...

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Bibliographic Details
Main Authors: Angelos Halaris, Daniel Hain, Rebecca Law, Lisa Brown, David Lewis, Maria Filip
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Bipolar depression
Treatment resistance
Escitalopram
Celecoxib
C-reactive protein
Single nucleotide polymorphism
Online Access:http://www.sciencedirect.com/science/article/pii/S266635462300039X

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