An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine

An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine

Human cytomegalovirus (HCMV) infection is associated with severe disease conditions either following congenital transmission of the virus or viral reactivation in immunosuppressed individuals. Consequently, the establishment of a protective vaccine is of high medical need. Several candidates have be...

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Bibliographic Details
Main Authors: Steffi Krauter, Nicole Büscher, Eric Bräuchle, Samira Ortega Iannazzo, Inessa Penner, Nadine Krämer, Patricia Gogesch, Simone Thomas, Marina Kreutz, Mario Dejung, Anja Freiwald, Falk Butter, Zoe Waibler, Bodo Plachter
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
human cytomegalovirus
vaccine
subviral particles
dense bodies
conditional expression
ddFKBP
Online Access:https://www.mdpi.com/2076-393X/10/8/1326

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