HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients

HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients

Human T cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a subset of infected subjects. Two viral proteins, Tax-1 and HTLV-1 basic leucine zipper factor (HBZ), play import...

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Bibliographic Details
Main Authors: Greta Forlani, Marco Baratella, Alessandra Tedeschi, Claudine Pique, Steve Jacobson, Roberto S. Accolla
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
HTLV-1
HBZ
Tax-1
HAM/TSP
asymptomatic carriers
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00819/full

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