A low-testosterone state associated with endometrioma leads to the apoptosis of granulosa cells.
Although endometriosis is suspected to be a cause of premature ovarian insufficiency (POI), the mechanism(s) underlying this process have not been elucidated. Recently, androgens were shown to promote oocyte maturation and to play a role in folliculogenesis. In addition, several reports have documen...
Main Authors: | Yoshihiro J Ono, Akiko Tanabe, Yoko Nakamura, Hikaru Yamamoto, Atsushi Hayashi, Tomohito Tanaka, Hiroshi Sasaki, Masami Hayashi, Yoshito Terai, Masahide Ohmichi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4275210?pdf=render |
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