CD44 connects autophagy decline and ageing in the vascular endothelium

CD44 connects autophagy decline and ageing in the vascular endothelium

Abstract The decline of endothelial autophagy is closely related to vascular senescence and disease, although the molecular mechanisms connecting these outcomes in vascular endothelial cells (VECs) remain unclear. Here, we identify a crucial role for CD44, a multifunctional adhesion molecule, in con...

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Bibliographic Details
Main Authors: Lu Zhang, Peichang Yang, Jingxuan Chen, Zhiqiang Chen, Zhihui Liu, Gaoqing Feng, Fangfang Sha, Zirui Li, Zaoyi Xu, Yating Huang, Xiaotong Shi, Xuebiao Li, Jiatian Cui, Chenyi Zhang, Pei Fan, Liuqing Cui, Yunpeng Shen, Guangzhou Zhou, Hongjuan Jing, Shiwei Ma
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41346-y

Internet

https://doi.org/10.1038/s41467-023-41346-y

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