SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice

SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice

Summary: Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorder, causing defects of social interaction and repetitive behaviors. Here, we identify a de novo heterozygous gene-truncating mutation of the Sentrin-specific peptidase1 (SENP1) gene in people with ASD without neur...

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Main Authors: Kan Yang, Yuhan Shi, Xiujuan Du, Jincheng Wang, Yuefang Zhang, Shifang Shan, Yiting Yuan, Ruoqing Wang, Chenhuan Zhou, Yuting Liu, Zilin Cai, Yanzhi Wang, Liu Fan, Huatai Xu, Juehua Yu, Jinke Cheng, Fei Li, Zilong Qiu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721014121

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http://www.sciencedirect.com/science/article/pii/S2211124721014121

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