Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy

AIM: To compare the ocular surface changes of one-site versus two-site phacotrabeculectomy in angle-closure glaucoma associated with cataract.<p>METHODS: This retrospective, randomized study included 52 patients(52 eyes)with coexisting angle-closure glaucoma and cataract. The patients were ran...

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Main Authors: Ming-Jie Jiang, Wei-Jie Fan
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-01-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2019/2/201902029.pdf
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author Ming-Jie Jiang
Wei-Jie Fan
author_facet Ming-Jie Jiang
Wei-Jie Fan
author_sort Ming-Jie Jiang
collection DOAJ
description AIM: To compare the ocular surface changes of one-site versus two-site phacotrabeculectomy in angle-closure glaucoma associated with cataract.<p>METHODS: This retrospective, randomized study included 52 patients(52 eyes)with coexisting angle-closure glaucoma and cataract. The patients were randomly divided into 2 groups: one group had the phacotrabeculectomy in the superior quadrant through the same incision(one-site group; <i>n</i>=26), while the other group had the trabeculectomy through a superior quadrant incision, and the phacoemulsification through another separate, temporal, clear corneal incision(two-site group; <i>n</i>=26). In each group, the values such as tear break-up time(BUT), Schirmer I test(SⅠt), and corneal fluoresce(FL)in staining score were measured at 1d, 1wk, 1mo and 3mo postoperatively.<p>RESULTS: All patients were operated under local anesthesia and followed up for 3mo. The SⅠt of two-site group and one-site group 1wk and 1mo postoperatively were significantly shorter than those before the operation(<i>P</i><0.01). The SⅠt of two-site group were significantly shorter than those of one-site group 1wk and 1mo postoperatively(<i>P</i><0.05). The FL scores of two-site group were significantly higher than those of one-site group 1wk postoperatively(<i>P</i><0.05). However, 1mo postoperatively, the FL scores of two groups were basically equal(<i>P</i>>0.05). Three months postoperatively,the BUT, SⅠt and FL were basically equal to the preoperative level(<i>P</i>>0.05).<p>CONCLUSION: Phacotrabeculectomy through two incisions is more likely to affect the ocular surface, and those abnormal related values appear in the early 1mo postoperatively.
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spelling doaj.art-6b83f7c52b9549288dbd4f98f56d84f32022-12-21T18:27:56ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232019-01-0119231031210.3980/j.issn.1672-5123.2019.2.29Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomyMing-Jie Jiang0Wei-Jie Fan1Department of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, ChinaDepartment of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, ChinaAIM: To compare the ocular surface changes of one-site versus two-site phacotrabeculectomy in angle-closure glaucoma associated with cataract.<p>METHODS: This retrospective, randomized study included 52 patients(52 eyes)with coexisting angle-closure glaucoma and cataract. The patients were randomly divided into 2 groups: one group had the phacotrabeculectomy in the superior quadrant through the same incision(one-site group; <i>n</i>=26), while the other group had the trabeculectomy through a superior quadrant incision, and the phacoemulsification through another separate, temporal, clear corneal incision(two-site group; <i>n</i>=26). In each group, the values such as tear break-up time(BUT), Schirmer I test(SⅠt), and corneal fluoresce(FL)in staining score were measured at 1d, 1wk, 1mo and 3mo postoperatively.<p>RESULTS: All patients were operated under local anesthesia and followed up for 3mo. The SⅠt of two-site group and one-site group 1wk and 1mo postoperatively were significantly shorter than those before the operation(<i>P</i><0.01). The SⅠt of two-site group were significantly shorter than those of one-site group 1wk and 1mo postoperatively(<i>P</i><0.05). The FL scores of two-site group were significantly higher than those of one-site group 1wk postoperatively(<i>P</i><0.05). However, 1mo postoperatively, the FL scores of two groups were basically equal(<i>P</i>>0.05). Three months postoperatively,the BUT, SⅠt and FL were basically equal to the preoperative level(<i>P</i>>0.05).<p>CONCLUSION: Phacotrabeculectomy through two incisions is more likely to affect the ocular surface, and those abnormal related values appear in the early 1mo postoperatively.http://ies.ijo.cn/cn_publish/2019/2/201902029.pdfphacotrabeculectomythe ocular surface changesone-sitetwo-site
spellingShingle Ming-Jie Jiang
Wei-Jie Fan
Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
Guoji Yanke Zazhi
phacotrabeculectomy
the ocular surface changes
one-site
two-site
title Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
title_full Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
title_fullStr Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
title_full_unstemmed Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
title_short Clinical observation of the ocular surface changes through one-site versus two-site phacotrabeculectomy
title_sort clinical observation of the ocular surface changes through one site versus two site phacotrabeculectomy
topic phacotrabeculectomy
the ocular surface changes
one-site
two-site
url http://ies.ijo.cn/cn_publish/2019/2/201902029.pdf
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