Soft Tissue Rosai-Dorfman Disease: Case report
Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofa...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sultan Qaboos University
2018-01-01
|
| Series: | Sultan Qaboos University Medical Journal |
| Subjects: | |
| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/2372 |
| _version_ | 1828494449817157632 |
|---|---|
| author | Rubyath C. Rajib Rajasekharan Pillai Ibrahim A. Sulaiman Ibrahim Al-Haddabi |
| author_facet | Rubyath C. Rajib Rajasekharan Pillai Ibrahim A. Sulaiman Ibrahim Al-Haddabi |
| author_sort | Rubyath C. Rajib |
| collection | DOAJ |
| description | Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions. |
| first_indexed | 2024-12-11T11:56:22Z |
| format | Article |
| id | doaj.art-6b84546d432b4d65bae66cc009ec1d0c |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-11T11:56:22Z |
| publishDate | 2018-01-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-6b84546d432b4d65bae66cc009ec1d0c2022-12-22T01:08:11ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282018-01-0117445245410.18295/squmj.2017.17.04.0122241Soft Tissue Rosai-Dorfman Disease: Case reportRubyath C. Rajib0Rajasekharan Pillai1Ibrahim A. Sulaiman2Ibrahim Al-Haddabi3Department of Pathology & Laboratory Medicine, Sultan Qaboos Hospital, Salalah, OmanDepartment of Pathology & Laboratory Medicine, Sultan Qaboos Hospital, Salalah, OmanDepartment of Pathology & Laboratory Medicine, Sultan Qaboos Hospital, Salalah, OmanDepartment of Pathology, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, OmanRosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.https://journals.squ.edu.om/index.php/squmj/article/view/2372histiocytosisrosai-dorfman diseaseemperipolesiss100 proteinscase reportoman. |
| spellingShingle | Rubyath C. Rajib Rajasekharan Pillai Ibrahim A. Sulaiman Ibrahim Al-Haddabi Soft Tissue Rosai-Dorfman Disease: Case report Sultan Qaboos University Medical Journal histiocytosis rosai-dorfman disease emperipolesis s100 proteins case report oman. |
| title | Soft Tissue Rosai-Dorfman Disease: Case report |
| title_full | Soft Tissue Rosai-Dorfman Disease: Case report |
| title_fullStr | Soft Tissue Rosai-Dorfman Disease: Case report |
| title_full_unstemmed | Soft Tissue Rosai-Dorfman Disease: Case report |
| title_short | Soft Tissue Rosai-Dorfman Disease: Case report |
| title_sort | soft tissue rosai dorfman disease case report |
| topic | histiocytosis rosai-dorfman disease emperipolesis s100 proteins case report oman. |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/2372 |
| work_keys_str_mv | AT rubyathcrajib softtissuerosaidorfmandiseasecasereport AT rajasekharanpillai softtissuerosaidorfmandiseasecasereport AT ibrahimasulaiman softtissuerosaidorfmandiseasecasereport AT ibrahimalhaddabi softtissuerosaidorfmandiseasecasereport |