Prediction of BRCA Gene Mutation in Breast Cancer Based on Deep Learning and Histopathology Images

Prediction of BRCA Gene Mutation in Breast Cancer Based on Deep Learning and Histopathology Images

BackgroundBreast cancer is one of the most common cancers and the leading cause of death from cancer among women worldwide. The genetic predisposition to breast cancer may be associated with a mutation in particular genes such as gene BRCA1/2. Patients who carry a germline pathogenic mutation in BRC...

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Bibliographic Details
Main Authors: Xiaoxiao Wang, Chong Zou, Yi Zhang, Xiuqing Li, Chenxi Wang, Fei Ke, Jie Chen, Wei Wang, Dian Wang, Xinyu Xu, Ling Xie, Yifen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
breast cancer
BRCA gene
deep learning
artificial intelligence
digital pathology
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.661109/full

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