Human neural stem cells genetically modified to overexpress Akt1 provide neuroprotection and functional improvement in mouse stroke model.

Human neural stem cells genetically modified to overexpress Akt1 provide neuroprotection and functional improvement in mouse stroke model.

In a previous study, we have shown that human neural stem cells (hNSCs) transplanted in brain of mouse intracerebral hemorrhage (ICH) stroke model selectively migrate to the ICH lesion and induce behavioral recovery. However, low survival rate of grafted hNSCs in the brain precludes long-term therap...

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Bibliographic Details
Main Authors:	Hong J Lee, Mi K Kim, Hee J Kim, Seung U Kim
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2679145?pdf=render

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