Adenosine A<sub>2A</sub> Receptors Shut Down Adenosine A<sub>1</sub> Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation

Adenosine A<sub>2A</sub> Receptors Shut Down Adenosine A<sub>1</sub> Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation

Adenosine operates a modulation system fine-tuning the efficiency of synaptic transmission and plasticity through A<sub>1</sub> and A<sub>2A</sub> receptors (A<sub>1</sub>R, A<sub>2A</sub>R), respectively. Supramaximal activation of A<sub>1</s...

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Bibliographic Details
Main Authors: Cátia R. Lopes, Francisco Q. Gonçalves, Simão Olaio, Angelo R. Tomé, Rodrigo A. Cunha, João Pedro Lopes
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
adenosine
release
synapse
A<sub>1</sub> receptor
A<sub>2A</sub> receptor
LTP
Online Access:https://www.mdpi.com/2218-273X/13/4/715

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