Primary Nongestational Choriocarcinoma of the Ovary

Pure primary ovarian choriocarcinoma is an extremely rare and aggressive tumor. It can be of gestational or nongestational in origin. The gestational type can arise from an ovarian pregnancy or can be of metastatic origin from uterine choriocarcinoma. The nongestational type is a very rare germ cell...

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Main Authors: AMM Shariful Alam, Syeda Nurjahan Bhuiyan, Md Rashid Un Nabi
Format: Article
Language:English
Published: Enam Medical College, Dhaka 2014-01-01
Series:Journal of Enam Medical College
Subjects:
Online Access:http://www.banglajol.info/index.php/JEMC/article/view/18070
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author AMM Shariful Alam
Syeda Nurjahan Bhuiyan
Md Rashid Un Nabi
author_facet AMM Shariful Alam
Syeda Nurjahan Bhuiyan
Md Rashid Un Nabi
author_sort AMM Shariful Alam
collection DOAJ
description Pure primary ovarian choriocarcinoma is an extremely rare and aggressive tumor. It can be of gestational or nongestational in origin. The gestational type can arise from an ovarian pregnancy or can be of metastatic origin from uterine choriocarcinoma. The nongestational type is a very rare germ cell neoplasm. It is important to distinguish between two types of choriocarcinomas as nongestational origin is highly malignant and has worse prognosis than gestational type. But it is very difficult to differentiate by routine histological examination. Nongestational choriocarcinoma has been found to be resistant to single agent chemotherapy. It occurs usually around 13 years of age and is mainly confined to females under 20. Here we report a case of primary pure nongestational choriocarcinoma of the ovary in an unmarried girl of 14 years, diagnosed in 2001 and treated successfully with surgery and combination chemotherapy and remained disease-free till last reporting in September 2013.
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spelling doaj.art-6b8f831e98a549739d3d8799090f3c822022-12-21T21:18:37ZengEnam Medical College, DhakaJournal of Enam Medical College2227-66882304-93162014-01-01415659http://dx.doi.org/10.3329/jemc.v4i1.18070Primary Nongestational Choriocarcinoma of the OvaryAMM Shariful Alam0Syeda Nurjahan Bhuiyan1Md Rashid Un Nabi2Professor, Department of Clinical Oncology, Enam Medical College & Hospital, Savar, Dhaka BangladesFormer Professor, Department of Obstetrics & Gynecology, Chittagong Medical College & Hospital, Chittagong Bangladesh Consultant Radiation Oncologist, United Hospital Ltd., Dhaka Bangladesh Pure primary ovarian choriocarcinoma is an extremely rare and aggressive tumor. It can be of gestational or nongestational in origin. The gestational type can arise from an ovarian pregnancy or can be of metastatic origin from uterine choriocarcinoma. The nongestational type is a very rare germ cell neoplasm. It is important to distinguish between two types of choriocarcinomas as nongestational origin is highly malignant and has worse prognosis than gestational type. But it is very difficult to differentiate by routine histological examination. Nongestational choriocarcinoma has been found to be resistant to single agent chemotherapy. It occurs usually around 13 years of age and is mainly confined to females under 20. Here we report a case of primary pure nongestational choriocarcinoma of the ovary in an unmarried girl of 14 years, diagnosed in 2001 and treated successfully with surgery and combination chemotherapy and remained disease-free till last reporting in September 2013.http://www.banglajol.info/index.php/JEMC/article/view/18070Nongestational; Choriocarcinoma; Ovary; Chemotherapy
spellingShingle AMM Shariful Alam
Syeda Nurjahan Bhuiyan
Md Rashid Un Nabi
Primary Nongestational Choriocarcinoma of the Ovary
Journal of Enam Medical College
Nongestational; Choriocarcinoma; Ovary; Chemotherapy
title Primary Nongestational Choriocarcinoma of the Ovary
title_full Primary Nongestational Choriocarcinoma of the Ovary
title_fullStr Primary Nongestational Choriocarcinoma of the Ovary
title_full_unstemmed Primary Nongestational Choriocarcinoma of the Ovary
title_short Primary Nongestational Choriocarcinoma of the Ovary
title_sort primary nongestational choriocarcinoma of the ovary
topic Nongestational; Choriocarcinoma; Ovary; Chemotherapy
url http://www.banglajol.info/index.php/JEMC/article/view/18070
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