Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection
<i>Background </i><i>and </i><i>objectives:</i> Children are at greater risk of upper respiratory tract infection (URTI), which can pose a higher risk of perioperative respiratory adverse events (PRAEs), than adults. The purpose of this study was to validate the C...
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MDPI AG
2022-09-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/10/1340 |
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| author | Hyo Sung Kim Young Sung Kim Byung Gun Lim Jae Hak Lee Jihyun Song Heezoo Kim |
| author_facet | Hyo Sung Kim Young Sung Kim Byung Gun Lim Jae Hak Lee Jihyun Song Heezoo Kim |
| author_sort | Hyo Sung Kim |
| collection | DOAJ |
| description | <i>Background </i><i>and </i><i>objectives:</i> Children are at greater risk of upper respiratory tract infection (URTI), which can pose a higher risk of perioperative respiratory adverse events (PRAEs), than adults. The purpose of this study was to validate the COLDS score as a pre-anesthetic risk assessment tool for predicting the possibility of PRAEs. <i>Materials and methods:</i> Children aged under 18 years and undergoing elective surgery were retrospectively included. Logistic regression analysis and the area under the receiver-operating characteristic (ROC) curve (AUC) were used to estimate the ability of the COLDS score to predict PRAEs. Propensity-matched comparison was evaluated using the cut-off value from the ROC curve. <i>Results:</i> Among the 6252 children, 158 children had a recent URTI and 34 cases of PRAEs were reported. Age, current symptoms, and COLDS score were found to be significant variables in predicting PRAEs. From the ROC curve, values of 0.652 (<i>p</i> = 0.007) for AUC and 12.5 for the cut-off value of the COLDS score were calculated. Propensity-matched comparison revealed that each and every component of COLDS contributed to the higher COLDS score group. In addition to higher COLDS score, younger age and current URTI symptoms were found to be significant risk factors for PRAEs. <i>Conclusions:</i> This study validated the predictive power of COLDS score as a risk assessment tool for children with URTI undergoing elective surgery under general anesthesia. |
| first_indexed | 2024-03-09T19:51:12Z |
| format | Article |
| id | doaj.art-6b90ae7222214f64a4ba606c49511810 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T19:51:12Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-6b90ae7222214f64a4ba606c495118102023-11-24T01:09:27ZengMDPI AGMedicina1010-660X1648-91442022-09-015810134010.3390/medicina58101340Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract InfectionHyo Sung Kim0Young Sung Kim1Byung Gun Lim2Jae Hak Lee3Jihyun Song4Heezoo Kim5Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, Korea<i>Background </i><i>and </i><i>objectives:</i> Children are at greater risk of upper respiratory tract infection (URTI), which can pose a higher risk of perioperative respiratory adverse events (PRAEs), than adults. The purpose of this study was to validate the COLDS score as a pre-anesthetic risk assessment tool for predicting the possibility of PRAEs. <i>Materials and methods:</i> Children aged under 18 years and undergoing elective surgery were retrospectively included. Logistic regression analysis and the area under the receiver-operating characteristic (ROC) curve (AUC) were used to estimate the ability of the COLDS score to predict PRAEs. Propensity-matched comparison was evaluated using the cut-off value from the ROC curve. <i>Results:</i> Among the 6252 children, 158 children had a recent URTI and 34 cases of PRAEs were reported. Age, current symptoms, and COLDS score were found to be significant variables in predicting PRAEs. From the ROC curve, values of 0.652 (<i>p</i> = 0.007) for AUC and 12.5 for the cut-off value of the COLDS score were calculated. Propensity-matched comparison revealed that each and every component of COLDS contributed to the higher COLDS score group. In addition to higher COLDS score, younger age and current URTI symptoms were found to be significant risk factors for PRAEs. <i>Conclusions:</i> This study validated the predictive power of COLDS score as a risk assessment tool for children with URTI undergoing elective surgery under general anesthesia.https://www.mdpi.com/1648-9144/58/10/1340COLDS scorepediatric anesthesiaperioperative respiratory adverse eventspre-anesthetic risk assessmentupper respiratory tract infection |
| spellingShingle | Hyo Sung Kim Young Sung Kim Byung Gun Lim Jae Hak Lee Jihyun Song Heezoo Kim Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection Medicina COLDS score pediatric anesthesia perioperative respiratory adverse events pre-anesthetic risk assessment upper respiratory tract infection |
| title | Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection |
| title_full | Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection |
| title_fullStr | Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection |
| title_full_unstemmed | Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection |
| title_short | Risk Assessment of Perioperative Respiratory Adverse Events and Validation of the COLDS Score in Children with Upper Respiratory Tract Infection |
| title_sort | risk assessment of perioperative respiratory adverse events and validation of the colds score in children with upper respiratory tract infection |
| topic | COLDS score pediatric anesthesia perioperative respiratory adverse events pre-anesthetic risk assessment upper respiratory tract infection |
| url | https://www.mdpi.com/1648-9144/58/10/1340 |
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