Silencing of LncRNA C1RL-AS1 Suppresses the Malignant Phenotype in Gastric Cancer Cells via the AKT/β-Catenin/c-Myc Pathway

Silencing of LncRNA C1RL-AS1 Suppresses the Malignant Phenotype in Gastric Cancer Cells via the AKT/β-Catenin/c-Myc Pathway

Purpose: Numerous studies have shown that lncRNAs play vital roles in the development and progression of cancer. However, investigations of lncRNAs in gastric cancer are limited and need to be further pursued.Materials and Methods: According to RNA-seq results of gastric cancer (GC) tissues, we iden...

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Bibliographic Details
Main Authors: Wu Zhen-Hua, Gong Yi-Wei, Zhao Li-Qin, Zhang Jie-Yun, Gong Zhe, Guo Wei-Jian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
lncRNA C1RL-AS1
malignancy
β-catenin
c-Myc
gastric cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01508/full

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