Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey
Abstract Background Although frailty is a common geriatric syndrome in old adults, a simple method to assess the degree of frailty in a person has not yet been established. In this study we have tried to establish the association between calf circumference (CC) and frailty among older Chinese people...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-022-03644-w |
| _version_ | 1811302186794090496 |
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| author | Ke Ying Xu Jun Jie Wang Jing Chen Xinxiu Zhao Ling Fang Yuan Qin Zhang |
| author_facet | Ke Ying Xu Jun Jie Wang Jing Chen Xinxiu Zhao Ling Fang Yuan Qin Zhang |
| author_sort | Ke Ying Xu |
| collection | DOAJ |
| description | Abstract Background Although frailty is a common geriatric syndrome in old adults, a simple method to assess the degree of frailty in a person has not yet been established. In this study we have tried to establish the association between calf circumference (CC) and frailty among older Chinese people. Methods We used the data obtained from the 2014 edition of the Chinese Longitudinal Healthy Longevity Survey; 1216 participants aged ≥60 years were included for the study. Body mass index, CC and waist circumference measurement data, and laboratory test results were collected. Frailty status was measured using the frailty index (FI). Participants were then classified into non-frail (FI < 0.25) and frail (FI ≥ 0.25) groups. Results There were 874 participants (71.9%) in the non-frail group and 342 (28.1%) in the frail group. The CC was significantly different between the two groups (31.54 ± 4.16 versus 28.04 ± 4.53, P < 0.001). Logistic regression analysis revealed that CC (odds ratio = 0.947, 95% confidence interval: 0.904–0.993, P = 0.023) was an independent impact factor associated with frailty. The CC value of 28.5 cm was considered the best cut-off value in women with area under the curve (AUC) was 0.732 (P < 0.001) and 29.5 cm in men with AUC was 0.592 (P = 0.004);We created a simple prediction model for frailty that included age,sex and CC: $$\textrm{Logit}(P)=-9.756+0.123\ast \textrm{Age}-0.512\ast \textrm{Sex}\left(\textrm{man}=1,\textrm{woman}=0\right)-0.053\ast \textrm{CC},$$ Logit ( P ) = - 9.756 + 0.123 * Age - 0.512 * Sex man = 1 , woman = 0 - 0.053 * CC , P = elogit(P) /1 + elogit(P), and AUC is 0.849 (P < 0.001). Conclusions CC is a convenient and predictable marker of frailty in older adults. |
| first_indexed | 2024-04-13T07:23:32Z |
| format | Article |
| id | doaj.art-6b90dfef58de4c20bfa7eccda1bb0a60 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-13T07:23:32Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-6b90dfef58de4c20bfa7eccda1bb0a602022-12-22T02:56:33ZengBMCBMC Geriatrics1471-23182022-12-012211910.1186/s12877-022-03644-wCalf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity surveyKe Ying Xu0Jun Jie Wang1Jing Chen2Xinxiu Zhao3Ling Fang Yuan4Qin Zhang5Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Psychiatry, Hangzhou Seventh People’s Hospital, HangzhouDepartment of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang UniversityAbstract Background Although frailty is a common geriatric syndrome in old adults, a simple method to assess the degree of frailty in a person has not yet been established. In this study we have tried to establish the association between calf circumference (CC) and frailty among older Chinese people. Methods We used the data obtained from the 2014 edition of the Chinese Longitudinal Healthy Longevity Survey; 1216 participants aged ≥60 years were included for the study. Body mass index, CC and waist circumference measurement data, and laboratory test results were collected. Frailty status was measured using the frailty index (FI). Participants were then classified into non-frail (FI < 0.25) and frail (FI ≥ 0.25) groups. Results There were 874 participants (71.9%) in the non-frail group and 342 (28.1%) in the frail group. The CC was significantly different between the two groups (31.54 ± 4.16 versus 28.04 ± 4.53, P < 0.001). Logistic regression analysis revealed that CC (odds ratio = 0.947, 95% confidence interval: 0.904–0.993, P = 0.023) was an independent impact factor associated with frailty. The CC value of 28.5 cm was considered the best cut-off value in women with area under the curve (AUC) was 0.732 (P < 0.001) and 29.5 cm in men with AUC was 0.592 (P = 0.004);We created a simple prediction model for frailty that included age,sex and CC: $$\textrm{Logit}(P)=-9.756+0.123\ast \textrm{Age}-0.512\ast \textrm{Sex}\left(\textrm{man}=1,\textrm{woman}=0\right)-0.053\ast \textrm{CC},$$ Logit ( P ) = - 9.756 + 0.123 * Age - 0.512 * Sex man = 1 , woman = 0 - 0.053 * CC , P = elogit(P) /1 + elogit(P), and AUC is 0.849 (P < 0.001). Conclusions CC is a convenient and predictable marker of frailty in older adults.https://doi.org/10.1186/s12877-022-03644-wCalf circumferenceFrailtyOld adults |
| spellingShingle | Ke Ying Xu Jun Jie Wang Jing Chen Xinxiu Zhao Ling Fang Yuan Qin Zhang Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey BMC Geriatrics Calf circumference Frailty Old adults |
| title | Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey |
| title_full | Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey |
| title_fullStr | Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey |
| title_full_unstemmed | Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey |
| title_short | Calf circumference predicts frailty in older adults: the Chinese longitudinal healthy longevity survey |
| title_sort | calf circumference predicts frailty in older adults the chinese longitudinal healthy longevity survey |
| topic | Calf circumference Frailty Old adults |
| url | https://doi.org/10.1186/s12877-022-03644-w |
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