Acellular Human Amniotic Fluid-Derived Extracellular Vesicles as Novel Anti-Inflammatory Therapeutics against SARS-CoV-2 Infection

Acellular Human Amniotic Fluid-Derived Extracellular Vesicles as Novel Anti-Inflammatory Therapeutics against SARS-CoV-2 Infection

The ongoing COVID-19 pandemic caused by SARS-CoV-2 is associated with acute respiratory distress syndrome (ARDS) and fatal pneumonia. Excessive inflammation caused by SARS-CoV-2 is the key driver of ARDS and lethal disease. Several FDA-approved drugs that suppress virus replication are in clinical u...

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Bibliographic Details
Main Authors: Debarati Chanda, Tania Del Rivero, Roshan Ghimire, Sunil More, Maria Ines Mitrani, Michael A. Bellio, Rudragouda Channappanavar
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Viruses
Subjects:
MA-CoV-2
acAF
AF-EVs
dysregulated immunity
cytokine storm
myeloid cells
Online Access:https://www.mdpi.com/1999-4915/16/2/273

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