Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy
Antimicrobial resistance is one of the most challenging public health problems worldwide, and integrated surveillance is a key aspect in a One Health control strategy. Additionally, <i>Salmonella</i> is the second most common zoonosis in Europe. We aimed to investigate the circulation of...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/11/12/1446 |
| _version_ | 1827637386266279936 |
|---|---|
| author | Valeria Listorti Aitor Garcia-Vozmediano Monica Pitti Cristiana Maurella Daniela Adriano Carlo Ercolini Monica Dellepiane Lisa Guardone Elisabetta Razzuoli |
| author_facet | Valeria Listorti Aitor Garcia-Vozmediano Monica Pitti Cristiana Maurella Daniela Adriano Carlo Ercolini Monica Dellepiane Lisa Guardone Elisabetta Razzuoli |
| author_sort | Valeria Listorti |
| collection | DOAJ |
| description | Antimicrobial resistance is one of the most challenging public health problems worldwide, and integrated surveillance is a key aspect in a One Health control strategy. Additionally, <i>Salmonella</i> is the second most common zoonosis in Europe. We aimed to investigate the circulation of <i>Salmonella</i> strains and their related antimicrobial resistance in human, environmental, and wild boar samples from the northwest of Italy, from 2018 to 2020, to obtain a more comprehensive epidemiological picture. <i>Salmonella</i> Typhimurium 1,4,[5],12:i:-, <i>S.</i> Veneziana and <i>S.</i> Newport were the most common serotypes occurring in humans, the environment, and wild boar, respectively. Antimicrobial resistance was rather common in <i>Salmonella</i> isolates, with those from human displaying the highest degree of resistance against sulfadiazine–sulfamerazine–sulfamethazine (>90% of resistance). Moreover, resistance against azithromycin were exclusively observed in environmental samples, while only 7.7% (95% CI = 1.6–20.8) of wild boar isolates experienced resistance against trimethoprim–sulfamethoxazole. Multidrug resistance concurrently involved up to seven antimicrobial classes in human isolates, including third-generation cephalosporins and fluoroquinolones. <i>Salmonella</i> Typhimurium in humans and serotypes Goldcoast and Rissen from environmental sources showed the highest levels of resistance. This study shows diverse antimicrobial resistance patterns in <i>Salmonella</i> strains isolated from different sources and gives a broad picture of antimicrobial resistance spread in wild animals, humans, and the environment. |
| first_indexed | 2024-03-09T15:59:21Z |
| format | Article |
| id | doaj.art-6b9353c29f1141c6a8b660d084d7e516 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T15:59:21Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-6b9353c29f1141c6a8b660d084d7e5162023-11-24T17:12:51ZengMDPI AGPathogens2076-08172022-11-011112144610.3390/pathogens11121446Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of ItalyValeria Listorti0Aitor Garcia-Vozmediano1Monica Pitti2Cristiana Maurella3Daniela Adriano4Carlo Ercolini5Monica Dellepiane6Lisa Guardone7Elisabetta Razzuoli8Section of Genoa, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Piazza Borgo Pila 39/24, 16129 Genoa, ItalySection of Turin, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via Bologna 148, 10154 Turin, ItalySection of Turin, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via Bologna 148, 10154 Turin, ItalySection of Turin, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via Bologna 148, 10154 Turin, ItalySection of Turin, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via Bologna 148, 10154 Turin, ItalySection of Savona, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via Martiri 6, 17056 Savona, ItalySection of La Spezia, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Via degli Stagnoni 96, 19100 La Spezia, ItalySection of Genoa, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Piazza Borgo Pila 39/24, 16129 Genoa, ItalySection of Genoa, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Piazza Borgo Pila 39/24, 16129 Genoa, ItalyAntimicrobial resistance is one of the most challenging public health problems worldwide, and integrated surveillance is a key aspect in a One Health control strategy. Additionally, <i>Salmonella</i> is the second most common zoonosis in Europe. We aimed to investigate the circulation of <i>Salmonella</i> strains and their related antimicrobial resistance in human, environmental, and wild boar samples from the northwest of Italy, from 2018 to 2020, to obtain a more comprehensive epidemiological picture. <i>Salmonella</i> Typhimurium 1,4,[5],12:i:-, <i>S.</i> Veneziana and <i>S.</i> Newport were the most common serotypes occurring in humans, the environment, and wild boar, respectively. Antimicrobial resistance was rather common in <i>Salmonella</i> isolates, with those from human displaying the highest degree of resistance against sulfadiazine–sulfamerazine–sulfamethazine (>90% of resistance). Moreover, resistance against azithromycin were exclusively observed in environmental samples, while only 7.7% (95% CI = 1.6–20.8) of wild boar isolates experienced resistance against trimethoprim–sulfamethoxazole. Multidrug resistance concurrently involved up to seven antimicrobial classes in human isolates, including third-generation cephalosporins and fluoroquinolones. <i>Salmonella</i> Typhimurium in humans and serotypes Goldcoast and Rissen from environmental sources showed the highest levels of resistance. This study shows diverse antimicrobial resistance patterns in <i>Salmonella</i> strains isolated from different sources and gives a broad picture of antimicrobial resistance spread in wild animals, humans, and the environment.https://www.mdpi.com/2076-0817/11/12/1446food-borne pathogens<i>Salmonella</i>surveillanceantimicrobial resistanceOne Health |
| spellingShingle | Valeria Listorti Aitor Garcia-Vozmediano Monica Pitti Cristiana Maurella Daniela Adriano Carlo Ercolini Monica Dellepiane Lisa Guardone Elisabetta Razzuoli Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy Pathogens food-borne pathogens <i>Salmonella</i> surveillance antimicrobial resistance One Health |
| title | Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy |
| title_full | Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy |
| title_fullStr | Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy |
| title_full_unstemmed | Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy |
| title_short | Antimicrobial Resistance of <i>Salmonella</i> Strains Isolated from Human, Wild Boar, and Environmental Samples in 2018–2020 in the Northwest of Italy |
| title_sort | antimicrobial resistance of i salmonella i strains isolated from human wild boar and environmental samples in 2018 2020 in the northwest of italy |
| topic | food-borne pathogens <i>Salmonella</i> surveillance antimicrobial resistance One Health |
| url | https://www.mdpi.com/2076-0817/11/12/1446 |
| work_keys_str_mv | AT valerialistorti antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT aitorgarciavozmediano antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT monicapitti antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT cristianamaurella antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT danielaadriano antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT carloercolini antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT monicadellepiane antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT lisaguardone antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly AT elisabettarazzuoli antimicrobialresistanceofisalmonellaistrainsisolatedfromhumanwildboarandenvironmentalsamplesin20182020inthenorthwestofitaly |