The Carotid Wallstent for the endovascular treatment of carotid artery stenosis
Aim: To report a retrospective, 15-years single-center experience about Carotid Artery Stenting (CAS) using the Carotid Wallstent in high surgical risk patients. Methods: Primary outcomes were procedural success, 30-day mortality and cerebrovascular complications, and long-term survival, neurologica...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-12-01
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| Series: | Interdisciplinary Neurosurgery |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751917301226 |
| _version_ | 1831787644741222400 |
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| author | Daniela Mazzaccaro Silvia Stegher Lorenzo Muzzarelli Giovanni Malacrida Giovanni Nano |
| author_facet | Daniela Mazzaccaro Silvia Stegher Lorenzo Muzzarelli Giovanni Malacrida Giovanni Nano |
| author_sort | Daniela Mazzaccaro |
| collection | DOAJ |
| description | Aim: To report a retrospective, 15-years single-center experience about Carotid Artery Stenting (CAS) using the Carotid Wallstent in high surgical risk patients. Methods: Primary outcomes were procedural success, 30-day mortality and cerebrovascular complications, and long-term survival, neurological complication and restenosis. P values < 0.05 were considered significant. Results: From January 2000 to June 2015, 560 patients underwent CAS using the Carotid Wallstent for either a symptomatic (22.6%) or an asymptomatic significant carotid stenosis. Primary success was achieved in 99.1% as 4 acute stent thrombosis occurred and in 1 case selective catheterization of the supra-aortic trunks was not possible due to extreme tortuosity. At 30 days, 7 TIAs and 9 strokes accounted for a 2.8% of neurological complication rate. There were 2 deaths unrelated to the procedure.At 10 years, survival was 71.2% ± 2.5%. Freedom from cerebrovascular events (TIA/stroke) at 10 years was 91.2% ± 1.9% for asymptomatic patients and 81.7% ± 5% for symptomatic patients (P = 0.008). Freedom from a restenosis >30% was estimated to be of 93.9% ± 1.3% at 10 years, being significantly affected by age (P = 0.01). Conclusion: In our experience the Carotid Wallstent was a safe and effective device for the treatment of both asymptomatic and symptomatic carotid stenosis in high surgical risk patients. Freedom from cerebrovascular events in the long term was worse in symptomatic patients. Keywords: Carotid artery stenting, Carotid Wallstent, Long-term results |
| first_indexed | 2024-12-22T13:34:58Z |
| format | Article |
| id | doaj.art-6b94661654f0432e8e695acce7889aff |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-12-22T13:34:58Z |
| publishDate | 2017-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-6b94661654f0432e8e695acce7889aff2022-12-21T18:24:05ZengElsevierInterdisciplinary Neurosurgery2214-75192017-12-0110108113The Carotid Wallstent for the endovascular treatment of carotid artery stenosisDaniela Mazzaccaro0Silvia Stegher1Lorenzo Muzzarelli2Giovanni Malacrida3Giovanni Nano4First Operative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; Corresponding author at: 1st Unit of Vascular Surgery, IRCCS Policlinico San Donato, Piazza Malan,1, 20097 San Donato Milanese (MI), Italy.First Operative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, ItalyFirst Operative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, ItalyFirst Operative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, ItalyFirst Operative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, ItalyAim: To report a retrospective, 15-years single-center experience about Carotid Artery Stenting (CAS) using the Carotid Wallstent in high surgical risk patients. Methods: Primary outcomes were procedural success, 30-day mortality and cerebrovascular complications, and long-term survival, neurological complication and restenosis. P values < 0.05 were considered significant. Results: From January 2000 to June 2015, 560 patients underwent CAS using the Carotid Wallstent for either a symptomatic (22.6%) or an asymptomatic significant carotid stenosis. Primary success was achieved in 99.1% as 4 acute stent thrombosis occurred and in 1 case selective catheterization of the supra-aortic trunks was not possible due to extreme tortuosity. At 30 days, 7 TIAs and 9 strokes accounted for a 2.8% of neurological complication rate. There were 2 deaths unrelated to the procedure.At 10 years, survival was 71.2% ± 2.5%. Freedom from cerebrovascular events (TIA/stroke) at 10 years was 91.2% ± 1.9% for asymptomatic patients and 81.7% ± 5% for symptomatic patients (P = 0.008). Freedom from a restenosis >30% was estimated to be of 93.9% ± 1.3% at 10 years, being significantly affected by age (P = 0.01). Conclusion: In our experience the Carotid Wallstent was a safe and effective device for the treatment of both asymptomatic and symptomatic carotid stenosis in high surgical risk patients. Freedom from cerebrovascular events in the long term was worse in symptomatic patients. Keywords: Carotid artery stenting, Carotid Wallstent, Long-term resultshttp://www.sciencedirect.com/science/article/pii/S2214751917301226 |
| spellingShingle | Daniela Mazzaccaro Silvia Stegher Lorenzo Muzzarelli Giovanni Malacrida Giovanni Nano The Carotid Wallstent for the endovascular treatment of carotid artery stenosis Interdisciplinary Neurosurgery |
| title | The Carotid Wallstent for the endovascular treatment of carotid artery stenosis |
| title_full | The Carotid Wallstent for the endovascular treatment of carotid artery stenosis |
| title_fullStr | The Carotid Wallstent for the endovascular treatment of carotid artery stenosis |
| title_full_unstemmed | The Carotid Wallstent for the endovascular treatment of carotid artery stenosis |
| title_short | The Carotid Wallstent for the endovascular treatment of carotid artery stenosis |
| title_sort | carotid wallstent for the endovascular treatment of carotid artery stenosis |
| url | http://www.sciencedirect.com/science/article/pii/S2214751917301226 |
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