Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions
Introduction The most common site of salivary gland tumors is the parotid gland. Computed tomography (CT), magnetic resonance imaging (MRI), and sonography are imaging modalities to differentiate benign from malignant parotid tumors. Objective The aim of this study is the evaluation of th...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2020-04-01
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| Series: | International Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1697005 |
| _version_ | 1818127744383320064 |
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| author | Masume Niazi Maryam Mohammadzadeh Kayvan Aghazadeh Hashem Sharifian Ebrahim Karimi Madjid Shakiba Maria Baniasadi Benyamin Rahmaty Suzan Adel Melorina Moharreri |
| author_facet | Masume Niazi Maryam Mohammadzadeh Kayvan Aghazadeh Hashem Sharifian Ebrahim Karimi Madjid Shakiba Maria Baniasadi Benyamin Rahmaty Suzan Adel Melorina Moharreri |
| author_sort | Masume Niazi |
| collection | DOAJ |
| description | Introduction The most common site of salivary gland tumors is the parotid gland. Computed tomography (CT), magnetic resonance imaging (MRI), and sonography are imaging modalities to differentiate benign from malignant parotid tumors.
Objective The aim of this study is the evaluation of the diagnostic value of perfusion CT for differentiating histological categorization of benign and malignant parotid tumors.
Methods A total of 29 patients with parotid neoplasms were enrolled in this study. Mean age and all CT perfusion variables (gradient and permeability, blood flow [BF], blood volume [BV], mean transit time [MTT], permeability surface [PS], maximum intensity projection [MIP], time-density curve [TDC], and time to peak [TTP]) were compared among three groups (malignant tumors [MTs], Warthin's tumor [WT] and pleomorphic adenomas [PA]).
Results The mean age of the patients was 55.9 ± 14.1 (26–77), and 15 of them were male (51.7%). Eleven lesions were PAs [37.9%], 8 lesions were WTs (27.6%0 and 10 lesions (34.5%) were MTs (6 acinic cell carcinomas [ACCs], 3 adenocystic carcinomas [AdCCs], and 1 mucoepidermoid carcinoma [MEC]). The mean age of the patients with WTs was 62 ± 7.5 years; 52 ± 14.2 for patients with Pas, and 55.2 ± 17.2 for those with MTs (p = 0.32). The mean MIP was 122.7 ± 12.2 in WT, while it was 80.5 ± 19.5 in PA, and 76.2 ± 27.1 in MTs (p < 0.001); The mean MIP for WT was higher than for PAs and MTs; the values of MTs and PAs were not statistically different. The average of BF, BV, and curve peak were higher in WTs in comparison with the other two groups, and curve time 2 and TTP were higher in PAs in comparison with MTs.
Conclusion Based on this study, perfusion CT of the parotid gland and its parameters can distinguish between benign and malignant parotid masses. |
| first_indexed | 2024-12-11T07:22:13Z |
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| id | doaj.art-6b963a05ab6c4d77bd4ebcb0e77127fa |
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| issn | 1809-9777 1809-4864 |
| language | English |
| last_indexed | 2024-12-11T07:22:13Z |
| publishDate | 2020-04-01 |
| publisher | Thieme Revinter Publicações Ltda. |
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| series | International Archives of Otorhinolaryngology |
| spelling | doaj.art-6b963a05ab6c4d77bd4ebcb0e77127fa2022-12-22T01:16:03ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642020-04-012402e160e16910.1055/s-0039-1697005Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid LesionsMasume Niazi0Maryam Mohammadzadeh1Kayvan Aghazadeh2Hashem Sharifian3Ebrahim Karimi4Madjid Shakiba5Maria Baniasadi6Benyamin Rahmaty7Suzan Adel8Melorina Moharreri9Department of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranDivision of Neuroradiology, Department of Radiology, Amir Aalam Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Radiology, Amir Aalam Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, IranDepartment of Radiology, Amir Aalam Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Otorhinolaryngology, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, IranIntroduction The most common site of salivary gland tumors is the parotid gland. Computed tomography (CT), magnetic resonance imaging (MRI), and sonography are imaging modalities to differentiate benign from malignant parotid tumors. Objective The aim of this study is the evaluation of the diagnostic value of perfusion CT for differentiating histological categorization of benign and malignant parotid tumors. Methods A total of 29 patients with parotid neoplasms were enrolled in this study. Mean age and all CT perfusion variables (gradient and permeability, blood flow [BF], blood volume [BV], mean transit time [MTT], permeability surface [PS], maximum intensity projection [MIP], time-density curve [TDC], and time to peak [TTP]) were compared among three groups (malignant tumors [MTs], Warthin's tumor [WT] and pleomorphic adenomas [PA]). Results The mean age of the patients was 55.9 ± 14.1 (26–77), and 15 of them were male (51.7%). Eleven lesions were PAs [37.9%], 8 lesions were WTs (27.6%0 and 10 lesions (34.5%) were MTs (6 acinic cell carcinomas [ACCs], 3 adenocystic carcinomas [AdCCs], and 1 mucoepidermoid carcinoma [MEC]). The mean age of the patients with WTs was 62 ± 7.5 years; 52 ± 14.2 for patients with Pas, and 55.2 ± 17.2 for those with MTs (p = 0.32). The mean MIP was 122.7 ± 12.2 in WT, while it was 80.5 ± 19.5 in PA, and 76.2 ± 27.1 in MTs (p < 0.001); The mean MIP for WT was higher than for PAs and MTs; the values of MTs and PAs were not statistically different. The average of BF, BV, and curve peak were higher in WTs in comparison with the other two groups, and curve time 2 and TTP were higher in PAs in comparison with MTs. Conclusion Based on this study, perfusion CT of the parotid gland and its parameters can distinguish between benign and malignant parotid masses.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1697005computed tomographymagnetic resonance imagingparotid neoplasmswarthin's tumorpleomorphic adenoma |
| spellingShingle | Masume Niazi Maryam Mohammadzadeh Kayvan Aghazadeh Hashem Sharifian Ebrahim Karimi Madjid Shakiba Maria Baniasadi Benyamin Rahmaty Suzan Adel Melorina Moharreri Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions International Archives of Otorhinolaryngology computed tomography magnetic resonance imaging parotid neoplasms warthin's tumor pleomorphic adenoma |
| title | Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions |
| title_full | Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions |
| title_fullStr | Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions |
| title_full_unstemmed | Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions |
| title_short | Perfusion Computed Tomography Scan Imaging in Differentiation of Benign from Malignant Parotid Lesions |
| title_sort | perfusion computed tomography scan imaging in differentiation of benign from malignant parotid lesions |
| topic | computed tomography magnetic resonance imaging parotid neoplasms warthin's tumor pleomorphic adenoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1697005 |
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