Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease—the human microbiome. This review article address...

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Main Authors: Mohamed Kamel, Sami Aleya, Majed Alsubih, Lotfi Aleya
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/14/2/217
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author Mohamed Kamel
Sami Aleya
Majed Alsubih
Lotfi Aleya
author_facet Mohamed Kamel
Sami Aleya
Majed Alsubih
Lotfi Aleya
author_sort Mohamed Kamel
collection DOAJ
description Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease—the human microbiome. This review article addresses the intricate relationship between the microbiome and infectious diseases and unravels its role as a crucial mediator of host–pathogen interactions. We explore the remarkable potential of harnessing this dynamic ecosystem to develop innovative treatment strategies that could revolutionize the management of infectious diseases. By exploring the latest advances and emerging trends, this review aims to provide a new perspective on combating infectious diseases by targeting the microbiome.
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spelling doaj.art-6ba09e6deae945f6b3e86e90f4a5f71f2024-02-23T15:23:53ZengMDPI AGJournal of Personalized Medicine2075-44262024-02-0114221710.3390/jpm14020217Microbiome Dynamics: A Paradigm Shift in Combatting Infectious DiseasesMohamed Kamel0Sami Aleya1Majed Alsubih2Lotfi Aleya3Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 11221, EgyptFaculty of Medecine, Université de Bourgogne Franche-Comté, Hauts-du-Chazal, 25030 Besançon, FranceDepartment of Civil Engineering, King Khalid University, Guraiger, Abha 62529, Saudi ArabiaLaboratoire de Chrono-Environnement, Université de Bourgogne Franche-Comté, UMR CNRS 6249, La Bouloie, 25030 Besançon, FranceInfectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease—the human microbiome. This review article addresses the intricate relationship between the microbiome and infectious diseases and unravels its role as a crucial mediator of host–pathogen interactions. We explore the remarkable potential of harnessing this dynamic ecosystem to develop innovative treatment strategies that could revolutionize the management of infectious diseases. By exploring the latest advances and emerging trends, this review aims to provide a new perspective on combating infectious diseases by targeting the microbiome.https://www.mdpi.com/2075-4426/14/2/217infectious diseaseshuman microbiomemicrobiome-targeted therapiestreatment approacheshost–pathogen interactions
spellingShingle Mohamed Kamel
Sami Aleya
Majed Alsubih
Lotfi Aleya
Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
Journal of Personalized Medicine
infectious diseases
human microbiome
microbiome-targeted therapies
treatment approaches
host–pathogen interactions
title Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
title_full Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
title_fullStr Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
title_full_unstemmed Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
title_short Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases
title_sort microbiome dynamics a paradigm shift in combatting infectious diseases
topic infectious diseases
human microbiome
microbiome-targeted therapies
treatment approaches
host–pathogen interactions
url https://www.mdpi.com/2075-4426/14/2/217
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AT lotfialeya microbiomedynamicsaparadigmshiftincombattinginfectiousdiseases