The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders

Reviewed are modern concepts concerning physiological role and mechanisms of brain functioning of the endocannabinoid signaling system comprising cannabinoid receptors, endocannabinoids and proteins participating in their synthesis, transport and degradation. The results of recent experimental studi...

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Main Author: V. P. Barkhatova
Format: Article
Language:English
Published: Research Center of Neurology 2017-02-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/413/315
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author V. P. Barkhatova
author_facet V. P. Barkhatova
author_sort V. P. Barkhatova
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description Reviewed are modern concepts concerning physiological role and mechanisms of brain functioning of the endocannabinoid signaling system comprising cannabinoid receptors, endocannabinoids and proteins participating in their synthesis, transport and degradation. The results of recent experimental studies showing an important role of the endocannabinoid system inmotor control and mechanisms of movement disorders in multiple sclerosis, Parkinsons disease and Huntingtons chorea are presented. In this context, investigation of possibilities of pharmacological correction of the endocannabinoid transmission should be considered as a novel and important field in experimental neurology with significant therapeutic potential.
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spelling doaj.art-6ba0f15644054adca317012a1c17363c2022-12-22T00:23:25ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0121283110.17816/psaic413313The endocannabinoid signaling system and new experimental approaches to the treatment of movement disordersV. P. Barkhatova0Research Center of Neurology, Russian Academy of Medical Sciences, MoscowReviewed are modern concepts concerning physiological role and mechanisms of brain functioning of the endocannabinoid signaling system comprising cannabinoid receptors, endocannabinoids and proteins participating in their synthesis, transport and degradation. The results of recent experimental studies showing an important role of the endocannabinoid system inmotor control and mechanisms of movement disorders in multiple sclerosis, Parkinsons disease and Huntingtons chorea are presented. In this context, investigation of possibilities of pharmacological correction of the endocannabinoid transmission should be considered as a novel and important field in experimental neurology with significant therapeutic potential.https://annaly-nevrologii.com/journal/pathID/article/viewFile/413/315endocannabinoid signaling systemmotor controlmovement disorderstreatment
spellingShingle V. P. Barkhatova
The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
Анналы клинической и экспериментальной неврологии
endocannabinoid signaling system
motor control
movement disorders
treatment
title The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
title_full The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
title_fullStr The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
title_full_unstemmed The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
title_short The endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
title_sort endocannabinoid signaling system and new experimental approaches to the treatment of movement disorders
topic endocannabinoid signaling system
motor control
movement disorders
treatment
url https://annaly-nevrologii.com/journal/pathID/article/viewFile/413/315
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