Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony
We report the self-limited nature of corneal opacification after accidental injection of Healon5 into the corneal stroma. A 52-year-old male with a new diagnosis of severe stage, primary open-angle glaucoma underwent successful trabeculectomy OS, which was complicated by ocular hypotony and shallow...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2020-07-01
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| Series: | Case Reports in Ophthalmology |
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| Online Access: | https://www.karger.com/Article/FullText/508604 |
| _version_ | 1817994887076773888 |
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| author | Michael Massengill Charles Richard Blake |
| author_facet | Michael Massengill Charles Richard Blake |
| author_sort | Michael Massengill |
| collection | DOAJ |
| description | We report the self-limited nature of corneal opacification after accidental injection of Healon5 into the corneal stroma. A 52-year-old male with a new diagnosis of severe stage, primary open-angle glaucoma underwent successful trabeculectomy OS, which was complicated by ocular hypotony and shallow anterior chamber (AC) on postoperative day 1. Healon5, a hyaluronic acid-containing viscoelastic device, was accidentally introduced into the corneal stroma during attempted injection into the AC. The cornea hydrodissected and opacified, leading to precipitous loss of best-corrected visual acuity (BCVA). The corneal opacification spontaneously resolved over a 7-month period without specific intervention. During this period, the patient also underwent cataract extraction with posterior chamber intraocular lens placement and YAG capsulotomy, after which his BCVA returned to approximately baseline. Though intrastromal injection of sodium hyaluronate-containing material has been reported elsewhere, this complication with Healon5 use specifically has yet to be described in the literature and may occur in any procedure involving Healon5 in the AC. This case report is important, since the precipitous loss of BCVA can be alarming to the ophthalmologist and the patient. The affected patient may be counseled that the opacification should improve with time. |
| first_indexed | 2024-04-14T01:58:02Z |
| format | Article |
| id | doaj.art-6ba26b7a73474a219b939c6afab2a94e |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-04-14T01:58:02Z |
| publishDate | 2020-07-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-6ba26b7a73474a219b939c6afab2a94e2022-12-22T02:18:57ZengKarger PublishersCase Reports in Ophthalmology1663-26992020-07-0111226326710.1159/000508604508604Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative HypotonyMichael MassengillCharles Richard BlakeWe report the self-limited nature of corneal opacification after accidental injection of Healon5 into the corneal stroma. A 52-year-old male with a new diagnosis of severe stage, primary open-angle glaucoma underwent successful trabeculectomy OS, which was complicated by ocular hypotony and shallow anterior chamber (AC) on postoperative day 1. Healon5, a hyaluronic acid-containing viscoelastic device, was accidentally introduced into the corneal stroma during attempted injection into the AC. The cornea hydrodissected and opacified, leading to precipitous loss of best-corrected visual acuity (BCVA). The corneal opacification spontaneously resolved over a 7-month period without specific intervention. During this period, the patient also underwent cataract extraction with posterior chamber intraocular lens placement and YAG capsulotomy, after which his BCVA returned to approximately baseline. Though intrastromal injection of sodium hyaluronate-containing material has been reported elsewhere, this complication with Healon5 use specifically has yet to be described in the literature and may occur in any procedure involving Healon5 in the AC. This case report is important, since the precipitous loss of BCVA can be alarming to the ophthalmologist and the patient. The affected patient may be counseled that the opacification should improve with time.https://www.karger.com/Article/FullText/508604corneal opacificationintrastromal injectionhealon5sodium hyaluronateocular hypotony |
| spellingShingle | Michael Massengill Charles Richard Blake Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony Case Reports in Ophthalmology corneal opacification intrastromal injection healon5 sodium hyaluronate ocular hypotony |
| title | Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony |
| title_full | Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony |
| title_fullStr | Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony |
| title_full_unstemmed | Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony |
| title_short | Corneal Opacification and Spontaneous Recovery following Injection of Healon5 into the Corneal Stroma during Intervention for Postoperative Hypotony |
| title_sort | corneal opacification and spontaneous recovery following injection of healon5 into the corneal stroma during intervention for postoperative hypotony |
| topic | corneal opacification intrastromal injection healon5 sodium hyaluronate ocular hypotony |
| url | https://www.karger.com/Article/FullText/508604 |
| work_keys_str_mv | AT michaelmassengill cornealopacificationandspontaneousrecoveryfollowinginjectionofhealon5intothecornealstromaduringinterventionforpostoperativehypotony AT charlesrichardblake cornealopacificationandspontaneousrecoveryfollowinginjectionofhealon5intothecornealstromaduringinterventionforpostoperativehypotony |