Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers

Despite the copious amount of research on the design and operation of micromixers, there are few works regarding manufacture technology aimed at implementation beyond academic environments. This work evaluates the viability of xurography as a rapid fabrication tool for the development of ultra-low c...

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Main Authors: J. Israel Martínez-López, Mauricio Mojica, Ciro A. Rodríguez, Héctor R. Siller
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/5/705
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author J. Israel Martínez-López
Mauricio Mojica
Ciro A. Rodríguez
Héctor R. Siller
author_facet J. Israel Martínez-López
Mauricio Mojica
Ciro A. Rodríguez
Héctor R. Siller
author_sort J. Israel Martínez-López
collection DOAJ
description Despite the copious amount of research on the design and operation of micromixers, there are few works regarding manufacture technology aimed at implementation beyond academic environments. This work evaluates the viability of xurography as a rapid fabrication tool for the development of ultra-low cost microfluidic technology for extreme Point-of-Care (POC) micromixing devices. By eschewing photolithographic processes and the bulkiness of pumping and enclosure systems for rapid fabrication and passively driven operation, xurography is introduced as a manufacturing alternative for asymmetric split and recombine (ASAR) micromixers. A T-micromixer design was used as a reference to assess the effects of different cutting conditions and materials on the geometric features of the resulting microdevices. Inspection by stereographic and confocal microscopy showed that it is possible to manufacture devices with less than 8% absolute dimensional error. Implementation of the manufacturing methodology in modified circular shape- based SAR microdevices (balanced and unbalanced configurations) showed that, despite the precision limitations of the xurographic process, it is possible to implement this methodology to produce functional micromixing devices. Mixing efficiency was evaluated numerically and experimentally at the outlet of the microdevices with performances up to 40%. Overall, the assessment encourages further research of xurography for the development of POC micromixers.
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spelling doaj.art-6ba2aeab202848f4bddaaceec80c593c2022-12-22T02:57:22ZengMDPI AGSensors1424-82202016-05-0116570510.3390/s16050705s16050705Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive MicromixersJ. Israel Martínez-López0Mauricio Mojica1Ciro A. Rodríguez2Héctor R. Siller3Tecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, N.L., MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, N.L., MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, N.L., MexicoTecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, N.L., MexicoDespite the copious amount of research on the design and operation of micromixers, there are few works regarding manufacture technology aimed at implementation beyond academic environments. This work evaluates the viability of xurography as a rapid fabrication tool for the development of ultra-low cost microfluidic technology for extreme Point-of-Care (POC) micromixing devices. By eschewing photolithographic processes and the bulkiness of pumping and enclosure systems for rapid fabrication and passively driven operation, xurography is introduced as a manufacturing alternative for asymmetric split and recombine (ASAR) micromixers. A T-micromixer design was used as a reference to assess the effects of different cutting conditions and materials on the geometric features of the resulting microdevices. Inspection by stereographic and confocal microscopy showed that it is possible to manufacture devices with less than 8% absolute dimensional error. Implementation of the manufacturing methodology in modified circular shape- based SAR microdevices (balanced and unbalanced configurations) showed that, despite the precision limitations of the xurographic process, it is possible to implement this methodology to produce functional micromixing devices. Mixing efficiency was evaluated numerically and experimentally at the outlet of the microdevices with performances up to 40%. Overall, the assessment encourages further research of xurography for the development of POC micromixers.http://www.mdpi.com/1424-8220/16/5/705xurographylaminationrapid fabricationmicromixersplitting and recombinationSARASARin-planelow-costmicrofluidicsPoint-of-Care
spellingShingle J. Israel Martínez-López
Mauricio Mojica
Ciro A. Rodríguez
Héctor R. Siller
Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
Sensors
xurography
lamination
rapid fabrication
micromixer
splitting and recombination
SAR
ASAR
in-plane
low-cost
microfluidics
Point-of-Care
title Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
title_full Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
title_fullStr Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
title_full_unstemmed Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
title_short Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices: Assessment of Passive Micromixers
title_sort xurography as a rapid fabrication alternative for point of care devices assessment of passive micromixers
topic xurography
lamination
rapid fabrication
micromixer
splitting and recombination
SAR
ASAR
in-plane
low-cost
microfluidics
Point-of-Care
url http://www.mdpi.com/1424-8220/16/5/705
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AT mauriciomojica xurographyasarapidfabricationalternativeforpointofcaredevicesassessmentofpassivemicromixers
AT ciroarodriguez xurographyasarapidfabricationalternativeforpointofcaredevicesassessmentofpassivemicromixers
AT hectorrsiller xurographyasarapidfabricationalternativeforpointofcaredevicesassessmentofpassivemicromixers