Targeting androgen receptor (AR) with a synthetic peptide increases apoptosis in triple negative breast cancer and AR‐expressing prostate cancer cell lines

Targeting androgen receptor (AR) with a synthetic peptide increases apoptosis in triple negative breast cancer and AR‐expressing prostate cancer cell lines

Abstract Background The androgen receptor (AR) has been studied as an approach to cancer therapy. Aims We used human breast cancer‐derived cells with high, low, and very low expression levels of AR, in addition to prostate cancer‐derived LNCaP and DU‐145 cells as a positive and negative controls to...

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Bibliographic Details
Main Authors: Mazdak Jamshidi, Fatemeh Keshavarzi, Sabrieh Amini, Ismail Laher, Ali Gheysarzadeh, Kambiz Davari
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cancer Reports
Subjects:
androgen receptor
anticancer peptide
apoptosis
breast cancer
dihydrotestosterone (DHT)
Online Access:https://doi.org/10.1002/cnr2.1922

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