Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train

Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train

Abstract Intraflagellar transport (IFT) trains, the polymers composed of two multi-subunit complexes, IFT-A and IFT-B, carry out bidirectional intracellular transport in cilia, vital for cilia biogenesis and signaling. IFT-A plays crucial roles in the ciliary import of membrane proteins and the retr...

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Bibliographic Details
Main Authors: Yuanyuan Ma, Jun He, Shaobai Li, Deqiang Yao, Chenhui Huang, Jian Wu, Ming Lei
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37208-2

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