Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train
Abstract Intraflagellar transport (IFT) trains, the polymers composed of two multi-subunit complexes, IFT-A and IFT-B, carry out bidirectional intracellular transport in cilia, vital for cilia biogenesis and signaling. IFT-A plays crucial roles in the ciliary import of membrane proteins and the retr...
Main Authors: | Yuanyuan Ma, Jun He, Shaobai Li, Deqiang Yao, Chenhui Huang, Jian Wu, Ming Lei |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-37208-2 |
Similar Items
-
The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport
by: Diego Huet, et al.
Published: (2014-04-01) -
Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis.
by: Bing Zhu, et al.
Published: (2017-02-01) -
Flagellar assembly in Chlamydomonas reinhardtii regulated by intraflagellar transport protein IFT81
by: SUN Juan
Published: (2015-08-01) -
Membrane association and remodeling by intraflagellar transport protein IFT172
by: Qianmin Wang, et al.
Published: (2018-11-01) -
Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex
by: Caitlyn L McCafferty, et al.
Published: (2022-11-01)