Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction

Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiolo...

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Main Author: Hidekatsu Fukuta
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-10-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articles/effects-of-exercise-training-on-cardiac-function
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author Hidekatsu Fukuta
author_facet Hidekatsu Fukuta
author_sort Hidekatsu Fukuta
collection DOAJ
description Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiology of HFpEF and is an important contributor to exercise intolerance in HFpEF patients. The effects of exercise training on left ventricular diastolic function in HFpEF patients have been examined in several randomised clinical trials. Meta-analysis of the trials indicates that exercise training can provide clinically relevant improvements in exercise capacity without significant change in left ventricular structure or function in HFpEF patients. Further studies are necessary to elucidate the exact mechanisms of exercise intolerance in HFpEF patients and to develop recommendations regarding the most effective type, intensity, frequency, and duration of training in this group.
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spelling doaj.art-6bab68ef69eb4937b19e392c39f760432024-04-20T16:01:59ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592020-10-01610.15420/cfr.2020.17Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection FractionHidekatsu Fukuta0Core Laboratory, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanNearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiology of HFpEF and is an important contributor to exercise intolerance in HFpEF patients. The effects of exercise training on left ventricular diastolic function in HFpEF patients have been examined in several randomised clinical trials. Meta-analysis of the trials indicates that exercise training can provide clinically relevant improvements in exercise capacity without significant change in left ventricular structure or function in HFpEF patients. Further studies are necessary to elucidate the exact mechanisms of exercise intolerance in HFpEF patients and to develop recommendations regarding the most effective type, intensity, frequency, and duration of training in this group.https://www.cfrjournal.com/articles/effects-of-exercise-training-on-cardiac-function
spellingShingle Hidekatsu Fukuta
Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
Cardiac Failure Review
title Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
title_full Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
title_fullStr Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
title_full_unstemmed Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
title_short Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction
title_sort effects of exercise training on cardiac function in heart failure with preserved ejection fraction
url https://www.cfrjournal.com/articles/effects-of-exercise-training-on-cardiac-function
work_keys_str_mv AT hidekatsufukuta effectsofexercisetrainingoncardiacfunctioninheartfailurewithpreservedejectionfraction