Unweaving the mitotic spindle: A focus on Aurora kinase inhibitors in lung cancer

Unweaving the mitotic spindle: A focus on Aurora kinase inhibitors in lung cancer

Lung cancer is one of the most aggressive malignancies, classified into two major histological subtypes: non-small cell lung cancer (NSCLC), that accounts for about 85% of new diagnosis, and small cell lung cancer (SCLC), the other 15%. In the case of NSCLC, comprehensive genome sequencing has allow...

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Bibliographic Details
Main Authors: Alessio Stefani, Geny Piro, Francesco Schietroma, Alessandro Strusi, Emanuele Vita, Simone Fiorani, Diletta Barone, Federico Monaca, Ileana Sparagna, Giustina Valente, Miriam Grazia Ferrara, Ettore D’Argento, Mariantonietta Di Salvatore, Carmine Carbone, Giampaolo Tortora, Emilio Bria
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
lung
cancer
oncology
Aurora kinase (AURK)
mitosis
AURK inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1026020/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1026020/full

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