Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines
Screening tools for sepsis and/or septic shock are designed to facilitate the early detection of sepsis. Various clinical parameters are used for screening, such as Systemic Inflammatory Response Syndrome (SIRS) criteria, vital signs, symptoms of infection, quick sequential organ failure (Q-SOFA) as...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2022-06-01
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| Series: | Медицина неотложных состояний |
| Subjects: | |
| Online Access: | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1502 |
| _version_ | 1827992751796387840 |
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| author | L.O. Maltseva V.M. Lisnycha N.A. Kazimirova |
| author_facet | L.O. Maltseva V.M. Lisnycha N.A. Kazimirova |
| author_sort | L.O. Maltseva |
| collection | DOAJ |
| description | Screening tools for sepsis and/or septic shock are designed to facilitate the early detection of sepsis. Various clinical parameters are used for screening, such as Systemic Inflammatory Response Syndrome (SIRS) criteria, vital signs, symptoms of infection, quick sequential organ failure (Q-SOFA) assessment outside the intensive care unit or Sequential (sepsis-related) Organ Failure Assessment (SOFA) criteria in the intensive care unit setting, Sepsis Risk Score and Severe Sepsis Risk Score, Sepsis Severity Score, National Early Warning Score (NEWS2), Modified Early Warning Score (MEWS2). The aim of the study is to thoroughly review the screening tools for sepsis and/or septic shock available in the literature in order to select the most optimal ones. Data analysis used to support the recommendations of The Third International Consensus Definitions for Sepsis and Septic Shock identified Q-SOFA as a predictor of lethal outcome in patients with known or suspected infection. Since then, numerous studies have investigated the use of Q-SOFA as a screening tool for sepsis: results are inconsistent. This test has been found to be more specific but less sensitive than the presence of 2 of the 4 SIRS criteria for the early detection of organ dysfunction caused by infection. Neither SIRS nor Q-SOFA have been found to be ideal screening tools for sepsis, and the clinician working at the bedside needs to understand the limitations of each. Only 24 % of infected patients had a Q-SOFA score of 2 or 3, but these patients accounted for 70 % of poor outcomes. Although the presence of a positive Q-SOFA should warn of the possibility of sepsis, given the low sensitivity of the test, it should not be used as the only screening tool. Similar results were obtained when comparing patients by NEWS2 and MEWS2. |
| first_indexed | 2024-04-10T04:12:43Z |
| format | Article |
| id | doaj.art-6bb01a85b0a14db889a940bf2a7d249e |
| institution | Directory Open Access Journal |
| issn | 2224-0586 2307-1230 |
| language | English |
| last_indexed | 2024-04-10T04:12:43Z |
| publishDate | 2022-06-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Медицина неотложных состояний |
| spelling | doaj.art-6bb01a85b0a14db889a940bf2a7d249e2023-03-12T15:00:56ZengZaslavsky O.Yu.Медицина неотложных состояний2224-05862307-12302022-06-01184515610.22141/2224-0586.18.4.2022.15021502Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelinesL.O. Maltseva0V.M. Lisnycha1N.A. Kazimirova2Дніпровський державний медичний університет, м. Дніпро, УкраїнаКЗ «Дніпропетровська обласна клінічна лікарня ім. І.І. Мечникова», м. Дніпро, УкраїнаКЗ «Дніпропетровська обласна клінічна лікарня ім. І.І. Мечникова», м. Дніпро, УкраїнаScreening tools for sepsis and/or septic shock are designed to facilitate the early detection of sepsis. Various clinical parameters are used for screening, such as Systemic Inflammatory Response Syndrome (SIRS) criteria, vital signs, symptoms of infection, quick sequential organ failure (Q-SOFA) assessment outside the intensive care unit or Sequential (sepsis-related) Organ Failure Assessment (SOFA) criteria in the intensive care unit setting, Sepsis Risk Score and Severe Sepsis Risk Score, Sepsis Severity Score, National Early Warning Score (NEWS2), Modified Early Warning Score (MEWS2). The aim of the study is to thoroughly review the screening tools for sepsis and/or septic shock available in the literature in order to select the most optimal ones. Data analysis used to support the recommendations of The Third International Consensus Definitions for Sepsis and Septic Shock identified Q-SOFA as a predictor of lethal outcome in patients with known or suspected infection. Since then, numerous studies have investigated the use of Q-SOFA as a screening tool for sepsis: results are inconsistent. This test has been found to be more specific but less sensitive than the presence of 2 of the 4 SIRS criteria for the early detection of organ dysfunction caused by infection. Neither SIRS nor Q-SOFA have been found to be ideal screening tools for sepsis, and the clinician working at the bedside needs to understand the limitations of each. Only 24 % of infected patients had a Q-SOFA score of 2 or 3, but these patients accounted for 70 % of poor outcomes. Although the presence of a positive Q-SOFA should warn of the possibility of sepsis, given the low sensitivity of the test, it should not be used as the only screening tool. Similar results were obtained when comparing patients by NEWS2 and MEWS2.https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1502sepsisseptic shockearly detectionscreening tools |
| spellingShingle | L.O. Maltseva V.M. Lisnycha N.A. Kazimirova Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines Медицина неотложных состояний sepsis septic shock early detection screening tools |
| title | Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines |
| title_full | Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines |
| title_fullStr | Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines |
| title_full_unstemmed | Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines |
| title_short | Screening tools developed for the early detection of sepsis and septic shock: a review of current guidelines |
| title_sort | screening tools developed for the early detection of sepsis and septic shock a review of current guidelines |
| topic | sepsis septic shock early detection screening tools |
| url | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1502 |
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