Most random gene expression signatures are significantly associated with breast cancer outcome.

Bridging the gap between animal or in vitro models and human disease is essential in medical research. Researchers often suggest that a biological mechanism is relevant to human cancer from the statistical association of a gene expression marker (a signature) of this mechanism, that was discovered i...

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Bibliographic Details
Main Authors: David Venet, Jacques E Dumont, Vincent Detours
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3197658?pdf=render