Methylisothiazolinone and Methylchloroisothiazolinone New Insights

Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high sensitising power and widespread use, MI is c...

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Main Authors: Ana Rita Rodrigues-Barata, Luis Conde-Salazar
Format: Article
Language:English
Published: European Medical Journal 2013-11-01
Series:European Medical Journal Dermatology
Subjects:
Online Access:https://emj.emg-health.com/wp-content/uploads/sites/2/2018/02/Methylisothiazolinone-and-Methylchloroisothiazolinone-New-Insights.pdf
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author Ana Rita Rodrigues-Barata
Luis Conde-Salazar
author_facet Ana Rita Rodrigues-Barata
Luis Conde-Salazar
author_sort Ana Rita Rodrigues-Barata
collection DOAJ
description Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high sensitising power and widespread use, MI is currently one of the most common causes of allergic contact dermatitis, both in our private lives and in the occupational field. As it was thought that MI had less sensitivity capacity, it started to be commercialised separately, and a new epidemic of sensitisation to these preservatives has been observed in recent years. MI should be included separately in the standard patch testing series. Also, the use of isothiazolinones should be revised, and legislative measures from the competent authorities should be implemented in order to resolve this problem.
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spelling doaj.art-6bb1c15fd6164b369d9422bab30ca2e82022-12-22T00:28:01ZengEuropean Medical JournalEuropean Medical Journal Dermatology2054-62112013-11-0121101105Methylisothiazolinone and Methylchloroisothiazolinone New InsightsAna Rita Rodrigues-Barata0Luis Conde-Salazar1Contact Dermatitis Unit, Department of Dermatology, Grupo Dermatología Pedro Jaén, Madrid, Spain Contact Dermatitis Unit, Department of Dermatology, Grupo Dermatología Pedro Jaén, Madrid, Spain Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high sensitising power and widespread use, MI is currently one of the most common causes of allergic contact dermatitis, both in our private lives and in the occupational field. As it was thought that MI had less sensitivity capacity, it started to be commercialised separately, and a new epidemic of sensitisation to these preservatives has been observed in recent years. MI should be included separately in the standard patch testing series. Also, the use of isothiazolinones should be revised, and legislative measures from the competent authorities should be implemented in order to resolve this problem.https://emj.emg-health.com/wp-content/uploads/sites/2/2018/02/Methylisothiazolinone-and-Methylchloroisothiazolinone-New-Insights.pdfcontact dermatitiscontact allergypreservativecosmeticsmethylisothiazolinonemethylchloroisothiazolinone
spellingShingle Ana Rita Rodrigues-Barata
Luis Conde-Salazar
Methylisothiazolinone and Methylchloroisothiazolinone New Insights
European Medical Journal Dermatology
contact dermatitis
contact allergy
preservative
cosmetics
methylisothiazolinone
methylchloroisothiazolinone
title Methylisothiazolinone and Methylchloroisothiazolinone New Insights
title_full Methylisothiazolinone and Methylchloroisothiazolinone New Insights
title_fullStr Methylisothiazolinone and Methylchloroisothiazolinone New Insights
title_full_unstemmed Methylisothiazolinone and Methylchloroisothiazolinone New Insights
title_short Methylisothiazolinone and Methylchloroisothiazolinone New Insights
title_sort methylisothiazolinone and methylchloroisothiazolinone new insights
topic contact dermatitis
contact allergy
preservative
cosmetics
methylisothiazolinone
methylchloroisothiazolinone
url https://emj.emg-health.com/wp-content/uploads/sites/2/2018/02/Methylisothiazolinone-and-Methylchloroisothiazolinone-New-Insights.pdf
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