Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences
2007-02-01
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| Series: | Urology Journal |
| Online Access: | http://www.urologyjournal.org/index.php/uj/article/view/105/104 |
| _version_ | 1819123400785788928 |
|---|---|
| author | Fahimeh Kamalian Mahdi Khabbaz Khoob Tayyebeh Kianoosh Mohammad Reza Parizadeh Nema Mohammadian Mohammad Reza Darabi Mahboub Hossein Ayatollahi |
| author_facet | Fahimeh Kamalian Mahdi Khabbaz Khoob Tayyebeh Kianoosh Mohammad Reza Parizadeh Nema Mohammadian Mohammad Reza Darabi Mahboub Hossein Ayatollahi |
| author_sort | Fahimeh Kamalian |
| collection | DOAJ |
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0 0 0 0;} @font-face {font-family:Tahoma; panose-1:2 11 6 4 3 5 4 4 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:1627400839 -2147483648 8 0 66047 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:"Times New Roman";} p.CharCharCharChar, li.CharCharCharChar, div.CharCharCharChar {mso-style-name:" Char Char Char Char"; mso-style-unhide:no; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; line-height:12.0pt; mso-line-height-rule:exactly; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Tahoma","sans-serif"; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman";} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} @page Section1 {size:612.0pt 792.0pt; margin:72.0pt 72.0pt 72.0pt 72.0pt; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.Section1 {page:Section1;} --> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} </style> <![endif]--> <p class="MsoNormal"><strong>Introduction:</strong> We evaluated the ratio of free to total prostate-specific antigen (PSA) and PSA to protein concentrations in saliva and serum of healthy men.</p> <p class="MsoNormal"><strong>Materials and Methods: </strong>Concentrations of protein, free PSA, and total PSA in serum and saliva were measured in 30 healthy men aged 42 to 73 years, and their ratios were compared between the two fluids.</p> <p class="MsoNormal"><strong>Results: </strong>There was a significant direct correlation between serum free-total PSA ratios of serum and saliva (<em>P</em> = .04) and between total PSA-protein ratios of serum and saliva (<em>P</em> = .02). Also, there were significant correlations between total and free PSA levels in saliva (<em>P</em> = .05) and between those in serum (<em>P</em> < .001). Significant inverse and direct correlations were detected between the body mass index and serum values of total PSA-protein (<em>P </em>= .04) and free-total PSA (<em>P </em>= .01), respectively.</p> <p class="MsoNormal"><strong>Conclusion: </strong>We can use saliva sample instead of serum sample for estimation of free-total PSA and total PSA-protein levels in men without prostate diseases. There is, however, a pressing need for much additional research in this area before the true clinical value of saliva as a diagnostic fluid can be determined.</p> |
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| issn | 1735-1308 1735-546X |
| language | English |
| last_indexed | 2024-12-22T07:07:45Z |
| publishDate | 2007-02-01 |
| publisher | Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences |
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| series | Urology Journal |
| spelling | doaj.art-6bb23d313b904f54ac7942326bb276172022-12-21T18:34:37ZengUrology and Nephrology Research Center, Shahid Beheshti University of Medical SciencesUrology Journal1735-13081735-546X2007-02-0144238241Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy MenFahimeh KamalianMahdi Khabbaz KhoobTayyebeh KianooshMohammad Reza ParizadehNema MohammadianMohammad Reza Darabi MahboubHossein Ayatollahi<!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>EN-US</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>AR-SA</w:LidThemeComplexScript> 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mso-fareast-font-family:"Times New Roman";} p.CharCharCharChar, li.CharCharCharChar, div.CharCharCharChar {mso-style-name:" Char Char Char Char"; mso-style-unhide:no; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; line-height:12.0pt; mso-line-height-rule:exactly; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Tahoma","sans-serif"; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman";} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} @page Section1 {size:612.0pt 792.0pt; margin:72.0pt 72.0pt 72.0pt 72.0pt; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.Section1 {page:Section1;} --> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} </style> <![endif]--> <p class="MsoNormal"><strong>Introduction:</strong> We evaluated the ratio of free to total prostate-specific antigen (PSA) and PSA to protein concentrations in saliva and serum of healthy men.</p> <p class="MsoNormal"><strong>Materials and Methods: </strong>Concentrations of protein, free PSA, and total PSA in serum and saliva were measured in 30 healthy men aged 42 to 73 years, and their ratios were compared between the two fluids.</p> <p class="MsoNormal"><strong>Results: </strong>There was a significant direct correlation between serum free-total PSA ratios of serum and saliva (<em>P</em> = .04) and between total PSA-protein ratios of serum and saliva (<em>P</em> = .02). Also, there were significant correlations between total and free PSA levels in saliva (<em>P</em> = .05) and between those in serum (<em>P</em> < .001). Significant inverse and direct correlations were detected between the body mass index and serum values of total PSA-protein (<em>P </em>= .04) and free-total PSA (<em>P </em>= .01), respectively.</p> <p class="MsoNormal"><strong>Conclusion: </strong>We can use saliva sample instead of serum sample for estimation of free-total PSA and total PSA-protein levels in men without prostate diseases. There is, however, a pressing need for much additional research in this area before the true clinical value of saliva as a diagnostic fluid can be determined.</p>http://www.urologyjournal.org/index.php/uj/article/view/105/104 |
| spellingShingle | Fahimeh Kamalian Mahdi Khabbaz Khoob Tayyebeh Kianoosh Mohammad Reza Parizadeh Nema Mohammadian Mohammad Reza Darabi Mahboub Hossein Ayatollahi Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men Urology Journal |
| title | Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men |
| title_full | Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men |
| title_fullStr | Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men |
| title_full_unstemmed | Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men |
| title_short | Ratios of Free to Total Prostate-Specific Antigen and Total Prostate Specific Antigen to Protein Concentrations in Saliva and Serum of Healthy Men |
| title_sort | ratios of free to total prostate specific antigen and total prostate specific antigen to protein concentrations in saliva and serum of healthy men |
| url | http://www.urologyjournal.org/index.php/uj/article/view/105/104 |
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