Licochalcone A Inhibits Prostaglandin E<sub>2</sub> by Targeting the MAPK Pathway in LPS Activated Primary Microglia

Licochalcone A Inhibits Prostaglandin E<sub>2</sub> by Targeting the MAPK Pathway in LPS Activated Primary Microglia

Neuroinflammation and oxidative stress are conditions leading to neurological and neuropsychiatric disorders. Natural compounds exerting anti-inflammatory and anti-oxidative effects, such as Licochalcone A, a bioactive flavonoid present in a traditional Chinese herb (licorice), might be beneficial f...

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Bibliographic Details
Main Authors: Harsharan Singh Bhatia, Matthias Apweiler, Lu Sun, Julian Baron, Ashwini Tirkey, Bernd L. Fiebich
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
Licochalcone A
flavonoids
Glycyrrhiza glabra
neuroinflammation
PGE<sub>2</sub>
arachidonic acid
Online Access:https://www.mdpi.com/1420-3049/28/4/1927

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