Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
Abstract Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Emba...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | The Journal of Clinical Hypertension |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jch.14611 |
| _version_ | 1797645162859462656 |
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| author | Xinxin Dai Li Kang Huiyu Ge |
| author_facet | Xinxin Dai Li Kang Huiyu Ge |
| author_sort | Xinxin Dai |
| collection | DOAJ |
| description | Abstract Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I2 statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I2 = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I2 = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I2 = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I2 = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I2 = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I2 = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted. |
| first_indexed | 2024-03-11T14:42:13Z |
| format | Article |
| id | doaj.art-6bb6ee233de54e818aa4d7934a79ecb4 |
| institution | Directory Open Access Journal |
| issn | 1524-6175 1751-7176 |
| language | English |
| last_indexed | 2024-03-11T14:42:13Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj.art-6bb6ee233de54e818aa4d7934a79ecb42023-10-30T13:30:24ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762023-01-0125151210.1111/jch.14611Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysisXinxin Dai0Li Kang1Huiyu Ge2Department of Ultrasound Medicine Beijing Chaoyang Hospital Capital Medical University Beijing ChinaDepartment of Ultrasound Medicine Beijing Chaoyang Hospital Capital Medical University Beijing ChinaDepartment of Ultrasound Medicine Beijing Chaoyang Hospital Capital Medical University Beijing ChinaAbstract Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I2 statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I2 = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I2 = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I2 = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I2 = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I2 = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I2 = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted.https://doi.org/10.1111/jch.14611Doppler flowmetrymeta‐analysisophthalmic arterypreeclampsiaultrasound |
| spellingShingle | Xinxin Dai Li Kang Huiyu Ge Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis The Journal of Clinical Hypertension Doppler flowmetry meta‐analysis ophthalmic artery preeclampsia ultrasound |
| title | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
| title_full | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
| title_fullStr | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
| title_full_unstemmed | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
| title_short | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
| title_sort | doppler parameters of ophthalmic artery in women with preeclampsia a meta analysis |
| topic | Doppler flowmetry meta‐analysis ophthalmic artery preeclampsia ultrasound |
| url | https://doi.org/10.1111/jch.14611 |
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