Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4<sup>+</sup> T-cells of Atopic Subjects

Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4<sup>+</sup> T-cells of Atopic Subjects

Optimal pre-analytical conditions for blood sample processing and isolation of selected cell populations for subsequent transcriptomic and epigenomic studies are required to obtain robust and reproducible results. This pilot study was conducted to investigate the potential effects of timing of CD4&l...

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Bibliographic Details
Main Authors: Fahd Alhamdan, Kristina Laubhahn, Christine Happle, Anika Habener, Adan C. Jirmo, Clemens Thölken, Raffaele Conca, Ho-Ryun Chung, Gesine Hansen, Daniel P. Potaczek, Bianca Schaub, Ruth Grychtol, Holger Garn
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
CD4<sup>+</sup> T-cells
transcriptomics
ChIP sequencing
histone modifications
epigenetics
Online Access:https://www.mdpi.com/2073-4409/11/19/2958

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