The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis
Prebiotics and postbiotics have gained attention as functional food additives due to their substantial influence on the gut microbiome and potential implications for human health on a broader scale. In addition, the number of patents for these additives has also increased, yet their functional class...
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/3/380 |
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| author | Tao Zang Lu Han Zhaoxiang Lu Lulu Tan Dunsheng Liang Xiaofan Shen Xiaoping Liao Yahong Liu Hao Ren Jian Sun |
| author_facet | Tao Zang Lu Han Zhaoxiang Lu Lulu Tan Dunsheng Liang Xiaofan Shen Xiaoping Liao Yahong Liu Hao Ren Jian Sun |
| author_sort | Tao Zang |
| collection | DOAJ |
| description | Prebiotics and postbiotics have gained attention as functional food additives due to their substantial influence on the gut microbiome and potential implications for human health on a broader scale. In addition, the number of patents for these additives has also increased, yet their functional classification has been problematic. In this study, we classified 2215 patents granted from 2001 to 2020 by functionality to enable predictions of future development directions. These patents encompassed subjects as diverse as feed supplementation, regulation of intestinal homeostasis, prevention of gastrointestinal ailments, targeted drug administration and augmentation of drug potency. The progression of patents issued during this time frame could be divided into three phases: occasional accounts prior to 2001, a period from 2001 to 2013 during which an average of 42 patents were issued annually, followed by a surge exceeding 140 patents annually after 2013. The latter increase has indicated that pre- and post-biotics have been recognized as biologically relevant. Patent mining therefore can enable forecasts of the future trajectory of these biologics and provide insights to evaluate their advancement. Moreover, this research is the first attempt to generalize and predict the directions of prebiotics and postbiotics using patent information and offers a comprehensive perspective for the potential utilization of prebiotics and postbiotics across a wide variety of fields. |
| first_indexed | 2024-03-08T03:51:45Z |
| format | Article |
| id | doaj.art-6bb7eeeefb1a4607b03acc39b375058c |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T03:51:45Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-6bb7eeeefb1a4607b03acc39b375058c2024-02-09T15:19:46ZengMDPI AGNutrients2072-66432024-01-0116338010.3390/nu16030380The History and Prediction of Prebiotics and Postbiotics: A Patent AnalysisTao Zang0Lu Han1Zhaoxiang Lu2Lulu Tan3Dunsheng Liang4Xiaofan Shen5Xiaoping Liao6Yahong Liu7Hao Ren8Jian Sun9Guangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaGuangdong Laboratory for Lingnan Modern Agriculture, State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, ChinaPrebiotics and postbiotics have gained attention as functional food additives due to their substantial influence on the gut microbiome and potential implications for human health on a broader scale. In addition, the number of patents for these additives has also increased, yet their functional classification has been problematic. In this study, we classified 2215 patents granted from 2001 to 2020 by functionality to enable predictions of future development directions. These patents encompassed subjects as diverse as feed supplementation, regulation of intestinal homeostasis, prevention of gastrointestinal ailments, targeted drug administration and augmentation of drug potency. The progression of patents issued during this time frame could be divided into three phases: occasional accounts prior to 2001, a period from 2001 to 2013 during which an average of 42 patents were issued annually, followed by a surge exceeding 140 patents annually after 2013. The latter increase has indicated that pre- and post-biotics have been recognized as biologically relevant. Patent mining therefore can enable forecasts of the future trajectory of these biologics and provide insights to evaluate their advancement. Moreover, this research is the first attempt to generalize and predict the directions of prebiotics and postbiotics using patent information and offers a comprehensive perspective for the potential utilization of prebiotics and postbiotics across a wide variety of fields.https://www.mdpi.com/2072-6643/16/3/380prebioticspostbioticspatent analysisgut microbiota |
| spellingShingle | Tao Zang Lu Han Zhaoxiang Lu Lulu Tan Dunsheng Liang Xiaofan Shen Xiaoping Liao Yahong Liu Hao Ren Jian Sun The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis Nutrients prebiotics postbiotics patent analysis gut microbiota |
| title | The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis |
| title_full | The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis |
| title_fullStr | The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis |
| title_full_unstemmed | The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis |
| title_short | The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis |
| title_sort | history and prediction of prebiotics and postbiotics a patent analysis |
| topic | prebiotics postbiotics patent analysis gut microbiota |
| url | https://www.mdpi.com/2072-6643/16/3/380 |
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